Abstract
Perchlorate anion (ClO4 −) has been found in drinking water supplies throughout the southwestern United States. It is primarily associated with releases of ammonium perchlorate by defense contractors, military operations, and aerospace programs. Ammonium perchlorate is used as a solid oxidant in missile and rocket propulsion systems. Traces of perchlorate are found in Chile saltpeter, but the use of such fertilizer has not been associated with large scale contamination. Although it is a strong oxidant, perchlorate anion is very persistent in the environment due to the high activation energy associated with its reduction. At high enough concentrations, perchlorate can affect thyroid gland functions, where it is mistakenly taken up in place of iodide. A safe daily exposure has not yet been set, but is expected to be released in 2002. Perchlorate is measured in environmental samples primarily by ion chromatography. It can be removed by anion exchange or membrane filtration. It is destroyed by some biological and chemical processes. The environmental occurrence, toxicity, analytical chemistry, and remediative approaches are discussed.
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References
Urbansky ET (1998): Perchlorate chemistry: Implications for analysis and remediation. Biorem J 2, 81–95
Espenson JH (2000): The problem and perversity of perchlorate. In: Perchlorate in the Environment, Urbansky ET (ed) Kluwer Academic/Plenum, New York, NY, Chapter 1
Abu-Omar MM, McPherson LD, Arias J, Béreau VM (2000): Clean and efficient catalytic reduction of perchlorate. Angew Chem Int Ed 39, 4310–4313
Earley JE, Sr., Tofan DC, Amadei GA (2000): Reduction of perchlorate ion by titanous ions in ethanolic solution. In: Perchlorate in the Environment, Urbansky ET (ed) Kluwer Academic/Plenum, New York, NY, Chapter 9
Burke PJ, Henrick K, McMillin DR (1982): Crystal and molecular structures of bis(4, 4, 6, 6-tetramethyl-2, 2′-bipyridyl) copper(I) perchlorate, bis(4, 4, 6, 6-tetramethyl-2, 2′-bipyridyl) copper(II) diperchlorate, and bis(4, 4, 6, 6-tetramethyl-2, 2′bipyridyl) copper(II) diperchlorate dihydrate. A search for copper(II) and copper(I) complexes with a common ligand environment. Inorg Chem 21, 1881–1886
US Environmental Protection Agency (1998): Drinking Water Contaminant Candidate List. Washington, DC, Doc No EPA/600/F-98/002
Gullick RW, LeChevallier MW, Barhorst TS (2001): Occurrence of perchlorate in drinking water sources. J Am Water Works Assoc 93 (1) 66–77
Ericksen GE (1983): The Chilean nitrate deposits. Am Sci 71, 366–374
Schilt AA (1979): Perchloric Acid and Perchlorates. GFS Chemicals, Inc., Columbus, OH
Urbansky ET, Brown SK, Magnuson ML, Kelty CA (2001): Perchlorate levels in samples of sodium nitrate fertilizer derived from Chilean caliche. Environ Pollut 112, 299–302
Lauterbach AR (2001): Reduction of perchlorate levels of sodium and potassium nitrates derived from natural caliche ore. Abstract Paper — Am Chem Soc Natl Meet, 222nd, AGRO-47
Susarla S, Collette TW, Garrison AW, Wolfe NL, McCutcheon SC (1999): Perchlorate identification in fertilizers. Environ Sci Technol 33, 3469–3472
Eldridge JE, Tsui DT, Mattie DR, Crown J, Scott R (1999): Perchlorate in Fertilizers. US Air Force Research Laboratories, Human Effectiveness Directorate, Deployment and Sustainment Division, Operational Toxicology Branch, Wright-Patterson AFB, OH, Doc No AFRL-HE-WP-TR-2000-0037
Urbansky ET, Magnuson ML, Kelty CA, Gu B, Brown GM (2000): Comment on ‘Perchlorate identification in fertilizers’ and the subsequent addition/correction. Environ Sci Technol 34, 4452–4453
Urbansky ET, Collette TW, Robarge WP, Hall WL, Skillen JM, Kane PF (2001): Survey of Fertilizers and Related Materials for Perchlorate (C1O4 −): Final Report. US Environmental Protection Agency, Cincinnati, OH, Doc No EPA/ 600/R-01/049
Wolff J (1998): Perchlorate and the thyroid gland. Pharmacol Rev 50, 89–105
Clark JJJ (2000): Toxicology of perchlorate. In: Perchlorate in the Environment, Urbansky ET (ed) Kluwer Academic/Plenum, New York, NY, Chapter 3
Li Z, Xiao LF, Byrd D, Deyhle GM, Sesser DE, Skeels MR, Lamm SH (2000): Neonatal thyroxine level and perchlorate in drinking water. J Occup Environ Med 42, 200–205
Lamm SH, Braverman LE, Xiao LF, Richman K, Pino S, Howearth G (1999): Thyroid health status of ammonium perchlorate workers: a cross-sectional occupational health study. J Occup Environ Med 41, 248–260
Lawrence JE, Lamm SH, Pino S, Richman K, Braverman LE (2000): The effect of short-term low-dose perchlorate on various aspects of thyroid function. Thyroid 10, 659–663
Crump C, Michaud P, T_llez R, Reyes C, Gonzalez G, Montgomery EL, Crump KS, Lobo G, Becerra C, Gibbs JP (2000): Does perchlorate in drinking water affect thyroid function in newborns or school-age children? J Occup Environ Med 42, 603–612
van Dam EWCM, Prummel MF, Wiersinga WM, Nikkeis RE (1993): Treatment of amiodarone-induced hypothyroidism with potassium perchlorate. Netherlands J Med 42, 21–24
Newnham HH, Topliss DJ, Le Grand BA, Chosich N, Harper RW, Stockigt JR (1988): Amiodarone-induced hyperthyroidism: assessment of the predictive value of biochemical testing and response to combined therapy using propylthiouracil and potassium perchlorate. Aust NZ J Med 18, 37–44
Martino E, Aghini-Lombardi F, Maiotti S, Lenziardi M, Baschieri L, Braverman LE, Pinchera A (1986): Treatment of amiodarone associated thyrotoxicosis by simultaneous administration of potassium perchlorate and methimazole. J Endocrinol Invest 9, 201–207
European Union (1982): EC Directive Relating to the Quality of Water Intended for Human Consumption. Office of Official Publications of the European Communities, Luxembourg, Doc No 80/778/EEC
Okamoto HS, Rishi DK, Steeber WR, Baumann FJ, Kusum Perera S (1999): Using ion chromatography to detect perchlorate. J Am Water Works Assoc 91 (10) 73–84
Hautman DP, Munch DJ, Eaton AD, Haghani AW (1999): Method 314.0. Determination of Perchlorate in Drinking Water Using Ion Chromatography, Revision 1. US Environmental Protection Agency, Cincinnati, OH, Doc No EPA/815/ B-99/003
US Environmental Protection Agency (2000): Method 9058. Determination of perchlorate using ion chromatography with chemical suppression conductivity detection. Washington, DC
Jackson PE, Laikhtman M, Rohrer JS (1999): Determination of trace level perchlorate in drinking water and ground water by ion chromatography. J Chromatogr A 850, 131–135
Jackson PE, Gokhale S, Rohrer JS (2000): Recent developments in the analysis of perchlorate using ion chromatography. In: Perchlorate in the Environment, Urbansky ET (ed) Kluwer Academic/Plenum, New York, NY, Chapter 5
De Borba BM, Rowe DW (2000): Determination of tracelevel perchlorate according to US EPA Method 314.0 using polyvinyl alochol gel resin. Am Lab 33 (9) 22–24
Urbansky ET (2000): Quantitation of perchlorate ion: Practices and advances applied to the analysis of common matrices. Crit Rev Anal Chem 30, 311–343
Ellington JJ, Evans JJ (2000): Determination of perchlorate at parts-per-billion levels in plants by ion chromatography. J Chromatogr A 898, 193–199
Ellington JJ, Wolfe NL, Garrison AW, Evans JJ, Avants JK, Teng Q (2001): Determination of perchlorate in tobacco plants and tobacco products. Environ Sci Technol 35, 3213–3218
Collette TW, Robarge WP, Urbansky ET (2001): Ion chromatographic determination of perchlorate: analysis of fertilizers and related materials. U.S. Environmental Protection Agency, National Risk Management Research Laboratory, Cincinnati, OH, Doc No EPA/600/R-01/026
Urbansky ET, Collette TW (2001): Comparison and evaluation of laboratory performance on a method for the determination of perchlorate in fertilizers. J Environ Monit 3, 454–462
De Borba BM, Urbansky ET (2002): Performance of poly(vinyl)alcohol gel columns on the ion Chromatographic determination of perchlorate in fertilizers. J Environ Monit 4(1) 149–155
Urbansky ET, Magnuson ML (2000): Sensitivity and selectivity enhancement in perchlorate anion quantitation using complexation-electrospray ionization-mass spectrometry. In: Perchlorate in the Environment, Urbansky ET (ed) Kluwer Academic/Plenum, New York, NY, Chapter 8
Urbansky ET, Magnuson ML, Freeman D, Jelks C (1999): Quantitation of perchlorate ion by electrospray ionization mass spectrometry (ESI-MS) using stable association complexes with organic cations and bases to enhance selectivity. J Anal At Spectrom 14, 1861–1866
Urbansky ET, Gu B, Magnuson ML, Brown GM, Kelty CA (2000): Survey of bottled waters for perchlorate by electrospray ionization mass spectrometry (ESI-MS) and ion chromatography (IC). J Sci Food Agric 80, 1798–1804
Magnuson ML, Urbansky ET, Kelty CA (2000): Determination of perchlorate at trace levels in drinking water by ionpair extraction with electrospray ionization mass spectrometry. Anal Chem 72, 25–29
Magnuson ML, Urbansky ET, Kelty CA (2000): Microscale extraction of perchlorate in drinking water by ion-pair extraction with low-level detection by electrospray mass spectrometry. Talanta 52, 285–291
Koester CJ, Beller HR, Halden RU (2000): Analysis of perchlorate in groundwater by electrospray ionization mass spectrometry/mass spectrometry. Environ Sci Technol 34, 1862–1864
Handy R, Barnett DA, Purves RW, Horlick G, Guevremont R (2000): Determination of nanomolar perchlorate in water by ESI-FAIMS-MS. J Anal At Spectrom 15, 907–911
Ells B, Barnett DA, W, PR, Guevremont R (2000): Trace level determination of perchlorate in water matrices and human urine using ESI-FAIMS-MS. J Environ Monit 2, 393–397
Susarla S, Collette TW, Garrison AW, Wolfe NL, McCutcheon SC (2000): Correction/Addition for ‘Perchlorate identification in fertilizers’. Environ Sci Technol 34, 224
Williams TL, Martin RB, Collette TW (2001): Raman spectroscopic analysis of fertilizers and plant tissue for perchlorate. Appl Spectrosc 55, 967–983
Ader M, Coleman ML, Doyle SP, Stroud M, Wakelin D (2001): Methods for the stable isotopic analysis of chlorine in chlorate and perchlorate compounds. Anal Chem 73, 4946–4950
Logan BE (2001): Assessing the outlook for perchlorate remediation. Environ Sci Technol 35, 482A-487A
Urbansky ET, Schock MR (1999): Issues associated with managing the risks of perchlorate in the drinking water. J Environ Manage 56, 79–95
Logan BE (1998): A review of chlorateand perchlorate-respiring microorganisms. Biorem J 2, 69–79
Coates JD, Michaelidou U, Bruce RA, O’Connor SM, Crespi JN, Achenbach LA (1999): The ubiquity and diversity of dissimilatory (per)chlorate-reducing bacteria. Appl Environ Microbiol 65, 5234–5241
Coates JD, Michaelidou U, O’Connor SM, Bruce RA, Achenbach LA (2000): The diverse microbiology of (per)chlorate reduction. In: Perchlorate in the Environment, Urbansky ET (ed) Kluwer Academic/Plenum, New York, NY, Chapter 24
Kim K, Logan BE (2001): Microbial reduction of perchlorate in pure and mixed culture packed-bed bioreactors. Wat Res 35, 3071–3076
Miller JP, Logan BE (2000): Sustained perchlorate degradation in an autotrophic, gas-phase, packed-bed reactor. Environ Sci Technol 34, 3018–3022
Herman DC, Frankenberger WT, Jr. (1999): Bacterial reduction of perchlorate and nitrate in water. J Environ Qual 28, 1018–1024
Okeke BC, Giblin T, Frankenberger WF, Jr. (2001): Reduction of perchlorate and nitrate by salt tolerant bacteria. Environ Pollut 118, 357–363
Logan BE, Wu J, Unz RF (2001): Biological perchlorate reduction in high-salinity solutions. Wat Res 35, 3034–3038
Nzengung VA, Wang C, Harvey G (1999): Plant-mediated transformation of perchlorate into chloride. Environ Sci Technol 33, 1470–1478
Nzengung VA, Wang C (2000): Influences on phytoremediation of perchlorate-contaminated water. In: Perchlorate in the Environment, Urbansky ET (ed) Kluwer Academic/Plenum, New York, NY, Chapter 21
Susarla S, Bacchus ST, Wolfe NL, McCutcheon SC (1999): Phytotransformation of perchlorate and identification of metabolic products inMyriophyllum aquaticum. Int J Phytorem 1, 97–107
Susarla S, Bacchus ST, Wolfe NL, McCutcheon SC (1999): Phytotransformation of perchlorate using parrot-feather. Soil Groundwater Cleanup February/March, 20
Susarla S, Bacchus ST, McCutcheon SC, Wolfe NL (1999): Potential Species for Phytoremediation of Perchlorate. US Environmental Protection Agency, Athens, GA, Doc No EPA/ 600/R-99/069
Brown GM, Bonnesen PV, Moyer BA, Gu B, Alexandratos SD, Ober R, Dale JA, Plant S (2000): The design of selective resins for the removal of pertechnetate and perchlorate from groundwater. In: Perchlorate in the Environment, Urbansky ET (ed) Kluwer Academic/Plenum, New York, NY, Chapter 15
Gu B, Brown GM, Maya L, Lance MJ, Moyer BA (2001): Regeneration of perchlorate (ClO4 −)-loaded anion exchange resins by a novel tetrachloroferrate (FeCl4 −) displacement technique. Environ Sci Technol 35, 3363–3368
Batista JR, X, MF, Vieira AR (2000): The removal of perchlorate waters using ion-exchange resins. In: Perchlorate in the Environment, Urbansky ET (ed) Kluwer Academic/Plenum, New York, NY, Chapter 13
Venkatesh KR, Klara SM, Jennings DL, Wagner NJ (2000): Removal and destruction of perchlorate and other anions from ground water using the ISEP+ system. In: Perchlorate in the Environment, Urbansky ET (ed) Kluwer Academic/Plenum, New York, NY, Chapter 14
Taylor JS, Wiesner M (1999): Membranes. In: Water Quality and Treatment: A Handbook of Community Water Supplies, Letterman RD (ed) McGraw-Hill, New York, NY, Chapter 11
Smith PN, Theodorakis CW, Anderson TA, Kendall RJ (2001): Preliminary assessment of perchlorate in ecological receptors at the Longhorn Army Ammunition Plant (LHAAP), Karnack, Texas. Ecotoxicology 10, 305–313
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Urbansky, E.T. Perchlorate as an environmental contaminant. Environ Sci & Potlut Res 9, 187–192 (2002). https://doi.org/10.1007/BF02987487
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DOI: https://doi.org/10.1007/BF02987487