Abstract
A phenyl propanoid derivative, dillapional(1) was found to be a antimicrobial principle of the stems ofFoeniculum vulgare (Umbelliferae) with MIC values of 125, 250 and 125/ againstBacillus subtilis, Aspergillus niger andCladosporium cladosporioides, respectively. A cou-marin derivative, scopoletin(2) was also isolated as marginally antimicrobial agent along with inactive compounds, dillapiol(3), bergapten(4), imperatorin(5) and psolaren(6) from this plant. The isolates 1-6 were not active against the Escherichia coli.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Ceska, O., Chaudgary, S. K., Warrington, P. J., Ashwood-Smith, M. J., Photoactive furocoumarins in fruits of some umbel-lifers.Phytochemistry, 26, 165–169 (1986).
Elgamal, M. H. A., Elewa, N. H., Elkhrisy, E. A. M. and Duddeck, H., 13C NMR chemical shift and carbon-proton coupling constants of some furocoumrins and furochromones.Phytochemistry, 18, 139–143 (1979).
Harkar, S., Razden, T. K., Waight, E. S., Steroids, chromone and coumrins fro.Angelica officinalis. Phytochemistry, 23, 419–426 (1984).
Kim, C. M., Sin, M. K., Lee, K. S. and Ahn, D. K., The dictionary of Chinese medicines, Jungdam press, Seoul, pp. 6597–6604, 1997.
Lee, K. H. and Soine, T. O., Coumain: Spectral studies on some linear furocoumarins,J. Pharm. Sci., 58, 681–683 (1969).
Ono, M., Ito, Y., Ishikawa, T., Kitajima, J., Tanaka, Y., Niiho, Y and Nohara, T., Five new monoterpene glycosides and other compounds from Foeniculi Fructus (Fruit o.Foeniculum vulgare Miller).Chem. Pharm. Bull., 44, 337–342 (1996).
Ono, M., Ito, Y., Kinjo, J., Yahara, S., Nohara, T. and Niiho, Y., Four new glycosides of stilbene trimer from Foeniculi Fructus (Fruit o.Foeniculum vulgare Miller).Chem. Pharm. Bull., 43, 868–871 (1995).
Orjala, J., Erdelmeier, C. A. J., Wright, A. D., Rali, T. and Sticher, O., Five new prenylated p-hydroxybenzoic acid derivatives with antimicrobial and molluscicidal activity fro.Piper aduncum leaves. Planta Med., 59, 546–551 (1993).
Steck W. and Mazurek, M., Identification of natural coumarins by nmr spectroscopy.Lloydia, 35, 418–439 (1972).
Tomar, S. S. and Mukerjee, Dillapional, a new constituent of Anethum sowa Roxb.Indian J. Chem., 20B, 723–724 (1981).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kwon, Y.S., Choi, W.G., Kim, W.J. et al. Antimicrobial constituents of foeniculum vulgare. Arch Pharm Res 25, 154–157 (2002). https://doi.org/10.1007/BF02976556
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02976556