Summary
Negative polarisation of the brain, previously shown to produce apathy and retardation in normal subjects, was given to four manic/hypomanic patients. In three of these a marked calming effect was noted, the fourth remaining relatively unaffected. The implications of these results were discussed and it was concluded that the method was probably effective in the treatment of this disorder and, because of facility and comfort of administration, particularly suited to the unco-operative patient.
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Carney, M.W.P. Negative polarisation of the brain in the treatment of manic states. I. J. Med. Sc. 2, 133–135 (1969). https://doi.org/10.1007/BF02958921
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DOI: https://doi.org/10.1007/BF02958921