Abstract
The pattern of uterine pressure cycles following oxytocin infusion was evaluated in near-term pregnant rats as a function of dietary zinc. Pressure cycles were monitored by a pressure transducer and polygraph linked to an intrauterine water-filled latex balloon, inserted on d 19 of gestation, in place of the right cranial fetus and its placenta. Oxytocin infusion on d 22 induced labor in all five zincdeficient rats, but the tracings revealed irregular, poorly synchronized, and/or low amplitude patterns, compared to controls. Excessive abdominal straining was required to accomplish fetal emergence in many instances. The results are interpreted as suggestive of diminished gap-junction formation.
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Lytton, F.D.C., Bunce, G.E. Dietary zinc and parturition in the rat. Biol Trace Elem Res 9, 151–163 (1986). https://doi.org/10.1007/BF02916523
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DOI: https://doi.org/10.1007/BF02916523