Abstract
Based on iron utilization, sensitivity to skin fatty acids, lipolytic and proteolytic activity the potential abilities ofStaphylococcus cohnii strains to colonize humans were evaluated. The investigation included 60 strains that belong to both subspecies,viz. S. cohnii ssp.cohnii andS. cohnii ssp.urealyticus. Strains were isolated from different sources of theIntensive Care Unit and from non-hospital environment. Most of the strains were multiple antibiotic-resistant. Strains of both subspecies revealed a relatively low iron requirement. These strains were capable of utilizing iron bound in oxo acids and from host iron-binding proteins.S. cohnii ssp.urealyticus were more effective in iron uptake thanS. cohnii ssp.cohnii. All investigated strains revealed sensitivity to skin fatty acids, butS. cohnii ssp.urealyticus strains were more resistant. Special features of strains of this subspecies promote colonization of humans.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Butcher G.H., Gillian K., Dyke K.G.H.J.: Sensitivity ofStaphylococcus aureus to unsaturated fatty acids.J. Gen. Microbiol.94, 290–286 (1976).
Downing D.T., Stewart M.E., Wertz W.P., Strauss J.S.: Essential fatty acids and acne.J. Am. Acad. Dermatol.14, 221–225 (1986).
Drechsel H., Thieken A., Reissbrodt R., Jung G., Winkelmann G.: β-Keto acids are novel siderophores in the generaProteus, Providencia, andMorganella produced by amino acid deaminases.J. Bacteriol.175, 2727–2733 (1993).
Freney J., Kloos W.E., Hajek V., Webster J.A., Bes M., Brun Y., Vernozy-Rozand C.: Recommended minimal standards for description of new staphylococcal species.Internat. J. Syst. Bacteriol.49, 489–502 (1999).
Heuck D., Beer W., Reissbrodt R.: Iron supply of staphylococci and micrococci by β-ketoacids.J. Med. Microbiol.433, 26–32 (1995).
Jarlov J.O., Hojbjerg T., Bussch-Sörensen J., Scheibel J., Moller J.K., Kolmos H.J., Wandall D.A.: Coagulase-negative staphylococci in Danish blood cultures: species distribution and antibiotic susceptibility.J. Hosp. Infect.32, 217–227 (1996).
Koneman E.W., Allen S.D., Janda W.M., Schreckenberger P.C., Winn W.C.:Diagnostic Microbiology, 5th ed., pp. 820–823. Lippincott-Raven, Philadelphia 1997.
Lacey R.W., Lord V.L.: Sensitivity of staphylococci to fatty acids: novel inactivation of linolenic acid by serum.J. Med. Microbiol.14, 41–49 (1981).
Lisiecki P., Sobiś-Glinkowska M., Mikucki J.: The animal body iron sources utilizedin vitro by staphylococci.Med. Dośw. Mikrobiol.49, 45–53 (1997).
Long J.P., Hart J., Albers W., Kapral, F.A.: The production of fatty acid modifying enzyme (FAME) and lipase by various staphylococcal species.J. Med. Microbiol.37, 232–234 (1992).
Marcelis J.H., Den Daas-Slagt H.J., Hoogkamp-Korstanje J.A.A.: Iron requirement and chelator production of staphylococci.Antonie van Leeuwenhoek44, 257–267 (1978).
Mastroianni A., Coronado O., Nanetti A., Manfredi R., Chido F.: Community-acquired pneumonia due toStaphylococcus cohnii in an HIV-infected patient: case report and review.Eur. J. Clin. Microbiol. Infect. Dis.14, 904–908 (1995).
Mickelsen P.A., Blackman E., Sparling P.F.: Ability ofNeisseria gonorrhoeae, Neisseria meningitidis and commensalNeisseria species to obtain iron from transferrin and iron compounds.Infect. Immun.33, 555–564 (1981).
Morton D.J., Williams P.: Utilization of transferrin-bound iron byHœmophilus species of human and porcine origin.FEMS Microbiol. Lett.65, 123–128 (1989).
Performance Standards for Antimicrobiol Disk Susceptibility Tests. Approved Standard. NCCLS Document M2-A6, 6th ed. (1997).
Petschow B.W., Batema R.P., Ford L.L.: Susceptibility ofHelicobacter pylori to bactericidal properties of medium-chain monoglycerides and free fatty acids.Antimicrob. Agents Chemother.40, 302–306 (1996).
Pidcock K.A., Wooten J.A., Daley B.A., Stull T.L.: Iron acquisition byHœmophilus influenzae.Infect. Immun.56, 721–725 (1988).
Szewczyk E.M., Piotrowski A., Różalska M.: Predominant staphylococci in the intensive care unit of a pædiatric hospital.J. Hosp. Infect.34, 145–154 (2000).
Szewczyk E.M., Różalska M.:Stapylococcus cohnii—resident of hospital environment: cell-surface features and resistance to antibiotics.Acta Microbiol. Pol.49, 121–133 (2000).
Taylor-Robinson D.:Staphylococcus cohnii andUreaplasma urealyticum in a neonate.Eur. J. Clin. Microbiol. Infect. Dis.18, 530 (1999).
Wang L.L., Johnson E.A.: Inhibition ofListeria monocytogenes by fatty aids and monoglycerides.Appl. Environ. Microbiol.58, 624–629 (1992).
Wooldridge K.G., Williams P.: Iron uptake mechanisms of pathogenic bacteria.FEMS Microbiol. Rev.12, 325–348 (1993).
Verweij-Van Vught A.M.J.J., Otto B.R., Namavar F., Sparrius M., Maclaren D.M.: Ability of bacteroides species to obtain iron from iron salts, hæm-compounds and transferrin.FEMS Microbiol. Lett.49, 223–228 (1988).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Waldon, E., Sobiś-Glinkowska, M. & Szewczyk, E.M. Evaluation of selected features ofStaphylococcus cohnii enabling colonization of humans. Folia Microbiol 47, 565–571 (2002). https://doi.org/10.1007/BF02818799
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02818799