Abstract
The energy vs distance balance of cell suspensions (in the presence and in the absence of extracellular biopolymer solutions) is studied, not only in the light of the classical Derjaguin-Landau-Verwey-Over-beek (DLVO) theory (which considered just the electrostatic (EL) and Lifshitz-van der Waals (LW) interactions), but also by taking electron-acceptor/electron-donor, or Lewis acid-base (AB) and osmotic (OS) interactions into account. Since cell surfaces, as well as many biopolymers tend to have strong monopolar electron-donor properties, they are able to engage in a strong mutual AB repulsion when immersed in a polar liquid such as water. The effects of that repulsion have been observed earlier in the guise of hydration pressure. The AB repulsion is, at close range, typically one or two orders of magnitude stronger than the EL repulsion, but its rate of decay is much steeper. In most cases, AB interactions are quantitatively the dominant factor in cell stability (when repulsive) and in “hydrophobic interactions” (when attractive). OS interactions exerted by extracellularly dissolved biopolymers are weak, but their rate of decay is very gradual, so OS repulsions engendered by biopolymer solutions may be of importance in certain long-range interactions. OS interactions exerted by biopolymers attached to cells or particles (e.g., by glycocalix glycoproteins), are very short-ranged and usually are negligibly small in comparison with the other interaction forces, in aqueous media.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Chaudhury, M. K. (1984), Ph. D. Thesis, State University of New York at Buffalo, Buffalo, NY.
Chaudhury, M. K., van Oss, C. J., and Good, R. J. (1988),J. Colloid Interface Sci. (submitted).
van Oss, C. J., Good, R. J., and Chaudhury, M. K. (1987),Separ. Sci. Technol. 22, 1–24.
van Oss, C. J., Chaudhury, M. K., and Good R. J. (1987),Adv. Colloid Interface Sci. 28, 35.
van Oss, C. J., Ju, L., Chaudhury, M. K., and Good, R. J. (1988),J. Colloid Interface Sci. (in press).
van Oss, C. J., Chaudhury, M. K., and Good, R. J. (1988),Chem. Revs. (in press).
Small, P. A. (1953),J. Appl. Chem. 3, 71.
Young, T. (1805),Phil. Trans. Roy. Soc. 95, 65.
van Oss, C. J., Chaudhury, M. K., and Good, R. J. (1987),Separ. Sci. Technol. 22, 1515.
van Oss, C. J., Good, R. J., and Chaudhury, M. K. (1987),J. Chromatog. 391, 53.
van Oss, C. J., Good, R. J., and Chaudhury, M. K. (1986),J. Prot. Chem. 5, 385.
van Oss, C. J., Chaudhury, M. K., and Good, R. J. (1987),Membrane Fusion, S. Ohki, ed., Plenum, New York (in press).
Righetti, P. G., van Oss, C. J., and Vanderhoff, J. W., eds. (1979),Electrokinetic Separation Methods, (Elsevier, Amsterdam.
Overbeek, J. Th. G. and Wiersema, P. H. (1967),Electrophoresis, M. Bier, ed., vol. 2, Academic, NY, p. 1.
Verwey, E. J. W. and Overbeek, J. Th. G. (1948),Theory of the Stability of Lyophobic Colloids, Elsevier, Amsterdam.
Overbeek, J. Th. G. (1952),Colloid Science, M. R. Kruyt, ed., vol. 1, Elsevier, Amsterdam, p. 245.
Kitahara, A. and Watanabe, A. (1984),Electrical Phenomena at Interfaces, Marcel Dekker, New York.
Hirtzel, C. S. and Rajagopalan, R. (1985),Advanced Topics in Colloidal Phenomena, Notes Pub., Park Ridge, NJ, p. 54.
Chan, D. Y. C., Mitchell, D. J., Ninham, B. W., and Pailthorpe, B. A. (1979),Water, F. Franks, ed., vol. 6, Plenum, NY, p. 239.
LeNeveu, D. M., Rand, R. P., and Parsegian, V. A. (1977),Biophys. J. 18, 209.
Parsegian, V. A., Rand, R. P., and Raw, D. C. (1985),Chemica Scripta 25, 28.
van Oss, C. J. and Good, R. J. (1988),J. Protein Chem. 7, 179.
Ruckenstein, E. and Schiby, D. (1983),Chem. Phys. Lett. 95, 439.
Claesson, P. M., Blom, C. E., Herden, P. C., and Ninham, B. W. (1986),J. Colloid Interface Sci. 114, 234.
Pashley, R. M., McGuiggan, P. M., Ninham, B. W., and Evans, D. F. (1986),Science 229, 1088.
Edberg, S. C., Bronson, P. M., and van Oss, C. J. (1972),Immunochemistry 9, 273.
Hiementz, P. C. (1986),Principles of Colloid and Surface Chemistry, Marcel Dekker, NY, p. 266.
van Oss, C. J. and Absolom, D. R. (1985),J. Dispersion Sci. Technol. 6, 131.
van Oss, C. J. and Bronson, P. M. (1970),Separ. Sci. 5, 63.
Good, R. J. (1979),Surface and Colloid Science, R. J. Good and R. R. Stromberg, eds., vol. 11, Plenum, NY, p. 1.
van Oss, C. J., Fike, R. M., Good, R. J., and Reinig, J. M. (1974),Analyt. Biochem. 60, 242.
van Oss, C. J., Gillman, C. F., and Neumann, A. W. (1975),Phagocytic Engulfment and Cell Adhesiveness, Marcel Dekker, NY.
van Oss, C. J. (1985),J. Dispersion Sci. Technol. 6, 139.
van Oss, C. J. (1978),Ann. Rev. Microbiol. 32, 19.
van Oss, C. J. (1986),Meth. Enzymol. 132, 3.
Absolom, D. R., van Oss, C. J., Zingg, W., and Neumann, A. W. (1982),J. Reticuloendothelial Soc. 31, 59.
van Oss, C. J., Absolom, D. R., and Neumann, A. W. (1984),The Reticuloendothelial System, S. M. Reichard and J. P. Filkins, eds., vol. 7A, Plenum, NY, p. 3.
Stinson, M. W. and van Oss, C. J. (1971),J. Reticuloendothelial Soc. 9, 503.
Tilley, D., Coakley, W. T., Gould, R. K., Payne, S. E., and Hewison, L. A. (1987),Eur. Biophys. J. (in press).
van Oss, C. J. and Coakley, W. T. (1988),Cell Biophys. (in press).
Brooks, D. E. and Seaman, G. V. F. (1973),J. Colloid Interface Sci. 43, 670.
Coakley, W. T., Hewison, L. A., and Tilley, D. (1985),Eur. Biophys. J. 13, 123.
van Oss, C. J., Mohn, J. F., and Cunningham, R. K. (1978),Vox. Sang. 34, 351.
Janzen, J. and Brooks, D. E. (1988),Interfacial Phenomena in Biological Systems, M. Bender, ed., Marcel Dekker, NY (in press).
Mohn, J. F. and Lambert, R. M., private communication.
Christenson, H. K. (1988),J. Dispersion Sci. Technol. 9, 171.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Van Oss, C.J. Energetics of cell-cell and cell-biopolymer interactions. Cell Biophysics 14, 1–16 (1989). https://doi.org/10.1007/BF02797387
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02797387