Abstract
Screening tests of fungal metabolites were performed for developing new types of antioxidants and synergists for tocopherol (Toc). Flavoglaucin has been found to be an excellent antioxidant and synergist. It is a phenolic compound isolated from mycelial mats ofEurotium chevalieri. Under autoxidation conditions, flavoglaucin remarkably synergized with Toc and stabilized many edible oils and fats. After the addition of flavoglaucin (0.05 %) the vegetable oils retained their original stabilities even after thermal treatment at 180 C for 25 hr. During the oxidation of lard containing Toc (0.04%) under the simulated deep-fat frying conditions, the addition of flavoglaucin didn’t retard the oxidative decomposition of Toc. However, the stability of lard always was higher in the presence of flavoglaucin than in its absence. Flavoglaucin is not mutagenic to Salmonella typhimurium TA 100 and TA 98.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Tagaki, T., and T. Iida, JAOCS 57:326 (1980).
Naito, S.; N. Yamaguchi and Y. Yokoo, J. Jpn. Soc. Food Sci. Technol. 28:291,465 (1981).
Fukuda, Y.; T. Osawa and M. Namiki, Ibid. 28:461 (1981).
Osawa, T., and M. Namiki, Agric. Biol. Chem. 45:735 (1981).
Hirosue, T.; H. Kawai and Y. Hosogai, J. Jpn. Soc. Food Sci. Technol. 29:418 (1982).
Nose, M., and N. Fujino, Ibid. 29:507 (1982).
Naito, S., and N. Yamaguchi, Ibid. 29:529 (1982).
Williams, N.S., and N.D. Harris, J. Food Sci. 48:644 (1983).
Okada, T., and N. Yamaguchi, J. Jpn. Oil Chem. Soc. 33:305 (1983).
Chipault, J.R., Food Eng. 29:134 (1957).
Saito, Y., J. Jpn. Oil Chem. Soc. 26:754 (1977).
Chang, S.S.; B. Ostric-Matijasevic, O.A.-L. Hsieh and C.-L. Huang, J. Food Sci. 42:1102 (1977).
Bracco, U.; J. Lolinger and J.L. Viret, JAOCS 58:686 (1981).
Brieskorn, C.H., and H.J. Domling, Z. Lebensmitt-Untersuch. 141:10 (1969).
Nakatani, N., and R. Inatani, Agric. Biol. Chem. 45:2385 (1981).
Wu, J.W.; M-H. Lee, C-T. Ho and S.S. Chang, JAOCS 59:339 (1982).
Inatani, R.; N. Nakatani, H. Fuwa and H. Seto, Agric. Biol. Chem. 46:1661 (1982).
Inatani, R.; N. Nakatani and H. Fuwa, Ibid. 47:521 (1983).
Zaika, L.L., and J.L. Smith, J. Sci. Fd. Agric. 26:1357 (1975).
Aoyama, T.; Y. Nakakita, M. Nakagawa and H. Sakai, Agric. Biol. Chem. 46:2369 (1982).
Ishikawa, Y., and E. Yuki, Ibid. 39:851 (1975).
Ishikawa, Y.; E. Yuki, H. Kato and M. Fujimaki, J. Jpn. Oil Chem. Soc. 26:765 (1977).
Ishikawa, Y., E. Yuki, H. Kato and M. Fujimaki, Agric. Biol. Chem. 42:703,711 (1978).
Ishikawa, Y., J. Jpn. Oil Chem. Soc. 29:844 (1980).
Ishikawa, Y.; K. Sugiyama and K. Nakabayashi, JAOCS in press (1984).
Yuki, E.; Y. Ishikawa and T. Yoshiwa, J. Jpn. Oil Chem. Soc. 23:497,714 (1974).
Hamasaki, T.; Y. Kimura, Y. Hatsuda and M. Nagao, Agric. Biol. Chem. 45:313 (1981).
Hamasaki, T.; M. Fukunaga, Y. Kimura and Y. Hatsuda, Ibid. 44:1685 (1980).
Hamasaki, T.; K. Nagayama and Y. Hatsuda, Ibid. 40:203 (1976).
Hamasaki, T., K. Nagayama and Y. Hatsuda, Ibid. 40:2487 (1976).
Hamasaki, T.; H. Kuwano, K. Isono, Y. Hatsuda, K. Fukuyama, T. Tsukihara and Y. Katsube, Ibid. 39:749 (1975).
Chexal, K.K.; C. Fouweather, J.S.E. Holker, T.J. Simpson and K. Young, J. Chem. Soc. Perkin Trans. I. 1974, p. 1584 [Ishida, M.; T. Hamasaki and Y. Hatsuda, Agric. Biol. Chem. 39:2181 (1975)].
Kitamura, Z.; U. Kurimoto and M. Yokoyama, J. Pharm. Soc. Jpn. 76:972 (1956).
Hamasaki, T.; Y. Sata, Y. Hatsuda, M. Tanabe and L.W. Cary, Tetrahedron Lett. No. 9:659 (1975).
Fukuyama, K.; T. Tsukihara, Y. Katsube, T. Hamasaki and Y. Hatsuda, Agric. Biol. Chem. 40:1053 (1976).
Hamasaki, T.; K. Nagayama and Y. Hatsuda, Ibid. 42:37 (1978).
Ishikawa, Y., JAOCS 59:505 (1982).
Martin, J.B., US Patent 2,634,213 (1953).
Yuki, E., and K. Morimoto, J. Jpn. Oil Chem. Soc. 31:915 (1982).
Yuki, E., and Y. Ishikawa, Ibid. 53:673 (1976).
Yoshihira, K.; C. Takahashi, S. Sekita and S. Natori, Chem. Pharm. Bull. 20:2727 (1972).
Turner, W.B., Fungal Metabolites, Academic Press Inc., London and New York, 1971, p. 141.
Winarno, F.G., JAOCS 56:363 (1979).
György, P.; K. Murata and Y. Sugimoto, JAOCS 51:377 (1974).
György, P., US Patent 3,855,256 (1974).
Ikehata, H.; M. Wakaizumi and K. Murata, Agric. Biol. Chem. 32:740 (1968).
Yoshida, H., and G. Kajimoto, J. Jpn. Soc. Food Nutr. 25:415 (1972).
Yamaguchi, N.; Y. Yokoo and M. Fujimaki, J. Jpn. Food Sci. Technol. 26:71 (1979).
Yamaguchi, N.; Y. Yokoo and M. Fujimaki, Ibid. 29:407 (1982).
Ishikawa, Y.; K. Morimoto and S. Iseki, Abstract of the Annual Meeting of Jpn. Oil Chem. Soc. 1982, p. 56.
Olcott, H.S., Lipids and Their Oxidation, edited by H.W. Schultz, E.A. Day and R.O. Sinnhuber, Avi Pub. Co., 1962, p. 173.
Motosugi, M.; S. Dohi, T. Suzuki and M. Ishikawa, J. Tech. Exp. Stn. Shizuoka Pref. (Jpn.). 25:117 (1981).
Ames, B.N., Science 221:1256 (1983).
Yuki, E., J. Jpn. Soc. Food Sci. Technol. 9:149 (1962).
Nakanishi, K., Jpn. Patent No. 48-7907 (1973).
Ishikawa, Y., and K. Itoh, J. Jpn. Oil Chem. Soc. 30:767 (1981).
Author information
Authors and Affiliations
About this article
Cite this article
Ishikawa, Y., Morimoto, K. & Hamasaki, T. Flavoglaucin, a metabolite ofEurotium chevalieri, its antioxidation and synergism with tocopherol. J Am Oil Chem Soc 61, 1864–1868 (1984). https://doi.org/10.1007/BF02540819
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02540819