Abstract
Hydrocarbon gases have been used previously as an index of lipid peroxidation in vivo and in vitro. In vitro experiments are reported on the formation of hydrocarbon gases from peroxidizing ω-3 and ω-6 fatty acids. Hydrocarbon gases were not related during a 20-hr peroxidation phase but were released following the decomposition of hydroperoxides by addition of excess ascorbic acid. The major hydrocarbon gas products in iron, copper, or hematin catalyzed peroxidation systems were ethane or ethylene from linolenic acid, and pentane from linoleic acid and arachidonic acid. Calculations of the ratios of hydrocarbon gases formed were based on fatty acid decrease and/or change in diene conjugation and peroxide values. Depending on the fatty acid, catalyst, and calculation basis used, pentane formation was a high as 1.3 mol %, ethanol 4.3 mol %, and ethylene 10.6 mol %.
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References
Evans, C.D., Proc. Flavor Chem Symp., Campbell Soup Company, 1961, p. 123.
Frankel, E.N., J. Nowakowska, and C.D. Evans, JAOCS 38:161 (1961).
Horvat, R.J., W.G. Lane, H. Ng, and A.D. Shepherd, Nature 203:523 (1964).
Evans, C.D., G.R. List, A. Dolev, D.G. McConnell, and R.L. Hoffmann, Lipids 2:432 (1967).
Forss, D.A., P. Angelini, M.L. Bazinet, and C. Meritt, Jr., JAOCS 44:141 (1967).
Evans, C.D., G.R. List, R.L. Hoffmann, and H.A. Moser, Ibid. 46:501 (1969).
Jarvi, P.K., G.D. Lee, D.R. Erickson, and E.A. Butkus, Ibid. 48:121 (1971).
Warner, K., C.D. Evans, G.R. List, B.K. Boundy, and W.F. Kwolek, J. Food Sci. 39:761 (1974).
Arnaud, M., and J.J. Wuhrmann, in “Work Documents, Topic 1b: Chemistry and Biochemistry of Food Deterioration”, IV International Congress of Food Science and Technology, Madrid, September 23–27, 1974, p. 1.
Plaa, G.L., and H. Witschi, Ann. Rev. Pharm. 16:125 (1976).
Chow, C.K., and A.L. Tappel, Lipids 7:578 (1972).
Tappel, A.L., in “Pathobiology of Cell Membranes,” Vol. 1, Edited by B.F. Trump and A.U. Arstila, Academic Press, New York, NY, 1975, p. 145.
Lieberman, M., and P. Hochstein, Science 152:213 (1966).
Lieberman, M., and L.W. Mapson, Nature 204:343 (1964).
Riely, C.A., G. Cohen, and M. Lieberman, Science 183:208 (1974).
Hafeman, D.G., and W.G. Hoekstra, J. Nutr. 107:656 (1977).
Hafeman, D.G., and W.G. Hoekstra, Ibid. 107:666 (1977).
Billard, C.J., E.E. Dumelin, and A.L. Tappel, Lipids 12:109 (1977).
Dumelin, E.E., C.J. Dillard, and A.L. Tappel, Arch. Environ. Health (In press).
O’Brien, P.J., Can. J. Biochem. 47:485 (1969).
Frankel, E.N., in “Symposium on Foods: Lipids and Their Oxidation,” Edited by H.W. Schultz, F.A. Day, and R.O. Sinnhuber, AVI Publishing Co., Westport, CT, 1962, p. 51.
Bunyan, J., E.A. Murrell, J. Green, and A.T. Diplock, Br. J. Nutr. 21:475 (1967).
Heath, R.L., and A.L. Tappel, Anal. Biochem. 76:184 (1976).
Sanders, T.H., H.E. Pattee, and J.A. Singleton, Lipids 10:568 (1975).
Sosnovsky, G., and D.J. Rawlinson, in “Organic Peroxides,” Vol. II, Edited by D. Swern, J. Wiley & Sons, New York, NY, 1971, pp. 159–172.
Huyser, E.S., “Free-Radical Chain Reactions,” J. Wiley & Sons, New York, NY 1970, pp. 225–229.
Pryor, W.A., “Free Radicals in Biology,” Vol. I, Academic Press, New York, NY, 1976, pp. 35–36.
Hiatt, R.R., CRC Crit. Rev. Food Sci. 7:1 (1975).
Tappel, A.L., Arch. Biochem. Biophys. 44:378 (1953).
Chan, H.W.S., F.A.A. Prescott, and P.A.T. Swoboda, JAOCS 53:572 (1976).
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Dumelin, E.E., Tappel, A.L. Hydrocarbon gases produced during in vitro peroxidation of polyunsaturated fatty acids and decomposition of preformed hydroperoxides. Lipids 12, 894–900 (1977). https://doi.org/10.1007/BF02533308
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DOI: https://doi.org/10.1007/BF02533308