Abstract
The finite-element method of stress analysis was applied, in its 3-dimensional form, to models of the left ventricular wall of two patients. The basic geometry and pressure changes were available from biplane angiographic and catheter data. A parametric study of the influence of the distribution of assumed wall stiffness was carried out on the computer models. By comparison with the experimental data the significance of the various changes could be assessed. For example, stiffness of the annulus fibrosus appears to exert a major influence on the deformation and volume change of the ventricle whereas that of the apex does not. The presence of infarcts in the region of the base are more significant than those near the apex. The spiral structure of the myocardium, and the ratio of longitudinal/circumferential stiffness are major determinants of diastolic wall position. These results appear to have appreciable clinical significance.
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Yettram, A.L., Vinson, C.A. & Gibson, D.G. Influence of the distribution of stiffness in the human left ventricular myocardium on shape change in diastole. Med. Biol. Eng. Comput. 17, 553–562 (1979). https://doi.org/10.1007/BF02440899
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DOI: https://doi.org/10.1007/BF02440899