Abstract
Tetrahymena pyriformis readily accumulated DDT and its metabolites from the medium initially containing 1 ppm of each compound. These compounds were accumulated in a decreasing order of DDD, DDE, o,p′-DDT, DDMU, and p,p′-DDT. DDT was metabolized to DDE, o,p′-DDT, and DDMU. DDD was metabolized to DDMU whereas o,p′-DDT, DDE and DDMU were not metabolized. When the organisms were transferred to toxicant free medium excretion of p,p′-DDT and its metabolite occurred in two phases: (a) rapid phase of elimination which was completed during the first 3 h and (b) slow phase of elimination which continued for another 21 h. The implications of these results are discussed.
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Agarwal, H.C., Saxena, D.M. & Lal, R. Accumulation and metabolism of DDT and its metabolites byTetrahymena . Water Air Soil Pollut 18, 441–447 (1982). https://doi.org/10.1007/BF02426051
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DOI: https://doi.org/10.1007/BF02426051