Summary
A patient with liver injury, probably due to chlorpromazine toxicity, is presented. Unusual features of this patient's illness included an extremely high and persistent elevation of alkaline phosphatase level without hyperbilirubinemia and lack of centrilobular bile stasis on liver biopsy.
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I wish to thank Dr. E. Eugene Owen for advice and encouragement in the preparation of this manuscript.
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Breuer, R.I. Chlorpromazine hepatotoxicity manifested by a selective and sustained rise of serum alkaline phosphatase activity. Digest Dis Sci 10, 727–731 (1965). https://doi.org/10.1007/BF02236073
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DOI: https://doi.org/10.1007/BF02236073