Conclusions
The presence of serum albumin in the gastric lumen can be readily diagnosed by paper electrophoresis of the gastric juice. While small amounts of albumin are present in the gastric juice under normal conditions, a massive leakage of serum albumin into the stomach occurs often in gastric cancer, Menetrier's disease, and in some cases of gastric atrophy. Paper electrophoresis of the gastric juice has definite clinical significance for the detection of these conditions.
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Supported by Grant-in-Aid A-68 (C7 and 8) from the Institute of Arthritis and Metabolic Diseases, N.I.H., U.S.P.H.S., and Grant E-18B from the American Cancer Society.
The initial phase of this work was performed with the technical assistance of Sallie E. Mitchell, A.B. Gastric juices of 3 patients with Menetrier's disease were kindly forwarded to us by Dr. F. Kern, Jr. of the V.A. Hospital, Denver, Colorado, Dr. H. D. Janowitz of the Mount Sinai Hospital, New York, and Dr. H. Colcher of the Goldwater Memorial Hospital (Columbia Division), New York. We wish here to express to them our appreciation of their interest and courtesy. Seven of the gastric juices of patients who had proved cases of gastric cancer (Table 1) were kindly forwarded to us by Dr. Joseph A. Buckwalter of the Department of Surgery, Iowa State University Medical School, Iowa City. The able assistance of Mrs. Antonina S. Glass in preparing the graphs and of Miss Lillian E. Palliser in editing this manuscript is gratefully acknowledged.
Illustrations so identified are from the forthcoming bookCurrent Gastroenterology, Paul B. Hoeber, Inc., Medical Division of Harper & Brothers, publishers.
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Glass, G.B.J., Ishimori, A. Passage of serum albumin into the stomach. Digest Dis Sci 6, 103–133 (1961). https://doi.org/10.1007/BF02231798
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DOI: https://doi.org/10.1007/BF02231798