Abstract
The authors applied frozen resin cracking after hexamethyldisilazane (HMDS) desiccation on the monkey optic disc region. The cracked face through the central part of the optic disc showed that the inner limiting membrane of the retina continued into the limiting membrane of Elschnig, and this, in turn, continued into the central meniscus of Kuhnt. At the disc margin the membrane was about 70 nm in thickness, due to a large fibrillar component. Elschnig's membrane was about 50 nm in thickness and was composed of both fibrils and flocculent material. The membrane covering the central meniscus of Kuhnt was about 20 nm in thickness. The number of fibrils here was very low, and the membrane consisted of flocculent material. The positive immunohistochemical stainings for GFA and vimentin of Elschnig's membrane and Kuhnt's meniscus were noteworthy. The positive staining disappeared when the membrane continued into the inner limiting membrane of the retina, supporting the different structural composition.
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References
Anderson DR (1970) Ultrastructure of the optic nerve head. Arch Ophthalmol 83:63–73
Anderson DR, Hoyt WF, Hogan MJ (1967) The fine structure of the astroglia in the human optic nerve and optic nerve head. Trans Am Ophthalmol Soc 65:275–305
Elschnig A (1901) Der normale Sehnerveneintritt des menschlichen Auges. Denkschriften der Mathematisch-Naturwissenschaftliche Classe der Kaiserlichen Akademie der Wissenschaften in Wien 70:219–303
Foos RY, Roth AM (1973) Surface structure of the optic nerve head. 2. Vitreopapillary attachments and posterior vitreous detachment. Am J Ophthalmol 76:662–671
Gartner J (1967) Elektronenmikroskopische Beobachtungen an der Papille des Rattenauges und beim Papillenödem des Menschen. Ophthalmologica (Basel) 153:367–384
Heegaard S, Jensen OA, Prause JU (1986) Hexamethyldisilazane in preparation of retinal tissue for scanning electron microscopy. Ophthalmic Res 18:203–208
Heegaard S, Jensen OA, Prause JU (1986) Structure and composition of the inner limiting membrane of the retina. Graefe's Arch Clin Exp Ophthalmol 224:355–360
Hogan MJ, Alvarado JA, Weddell JE (1971) Histology of the human eye. Saunders, Philadelphia London Toronto, pp 489–606
Kuhnt H (1879) Zur Kenntnis des Sehnerven und der Netzhaut. Graefe's Arch Clin Exp Ophthalmol 25:179–288
Roth AM, Foos RY (1972) Surface structure of the optic nerve head. 1. Epipapillary membranes. Am J Ophthalmol 74:977–985
Wolter JR (1959) Glia of the human retina. Am J Ophthalmol 48:370–393
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Heegaard, S., Jensen, O.A. & Prause, J.U. Structure of the vitread face of the monkey optic disc (Macacca mulatta). Graefe's Arch Clin Exp Ophthalmol 226, 377–383 (1988). https://doi.org/10.1007/BF02172971
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DOI: https://doi.org/10.1007/BF02172971