Summary
A study has been made of a specialS. sonnei serum obtained from Inst. Séroth. Suisse and the following results have been obtained. 1. The antiserum contains antibodies specific forS. sonnei and, in addition, antibodies reacting with crude antigens from other enteric bacteria in the hemagglutination test. 2. Mixtures of this antiserum in rather high dilutions and crude antigens from various enteric bacteria cause agglutination of normal erythrocytes. 3. The antibody responsible for this complex hemagglutination reaction is not directed against the 0 antigen nor the common antigen described byKunin, but rather against another antigen shared by certain enteric bacteria. 4. This particular antiserum has a lower content of an inhibitor which prevents erythrocyte modification than do normal rabbit serum or anotherS. sonnei antiserum.
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Study supported by Research Grant AI 00658, National Institute of Allergy and Infectious Diseases, U.S.P.H.S.
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Gorzynski, E.A., Brodhage, H. & Neter, E. Hemagglutination by mixtures of enterobacterial antigen and Shigella sonnei antiserum. Zeitschr. f. Hygiene. 150, 1–9 (1964). https://doi.org/10.1007/BF02162782
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DOI: https://doi.org/10.1007/BF02162782