Abstract
Congenital histiocytosis X involving multiple organs is a rare disease that causes rapid mortality in intrauterine and neonatal life. The diagnosis of histiocytosis X (Litterer-Siwe disease should be considered in a neonate with vesiculated crusting skin lesions. We present clinical, radiographic and histopathological findings in a neonate with congenital histiocytosis who died of respiratory failure due to diffuse infilteration of lungs with histiocytic cells.
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Yu CP, Tseng HH, Tu YC (1990) Congenital Letterer-Siwe disease with intrauterine fetal death: a case report and review of the literature. Taiwan I Hsueh Hui Tsa Chih 89: 806–810
Kagalwala TY, Kallapur SG, Rathore AS, Bharucha BA, Irani SF, Sane Y, Parikh DA (1989) Congenital histiocytosis X. Indian Pediatr 26: 292–296
Chu T, D'Angio GJ, Favara B, Ladisch S, Nesbit M, Pritchard J (1987) Histiocytosis syndromes in children. Lancet: I: 208–209
Dehner LP, Bamford JT, McDonald EC (1983) Spontaneous regression of congenital cutaneous histiocytosis X: report of a case with discussion of nosology and pathogenesis. Pediatr Pathol 1: 99–106
Marsh WL Jr, Lew SW, Heath VC, Lightsey AL (1983) Congenital self-healing histiocytosis-X. Am J Pediatr Hematol Oncol 5: 227–233
Lee RG, Braziel RM, Stenzel P (1990) Gastrointestinal involvement in Langerhans' cell histiocytosis (histiocytosis X): diagnosis by rectal biopsy. Mod Pathol 3: 154–157
Tamura T, Umetsu M, Motoya H, Yokoyama S (1980) Congenital Letterer-Siwe disease associated with protein losing enteropathy. Eur J Pediatr 135: 77–80
McClain K, Gehrz R, Grierson H, Purtilo D, Filipovich A (1988) Virus-associated histiocytic proliferations in children. Am J Pediatr Hematol Oncol 10: 196–205
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Vade, A., Hayani, A. & Pierce, K.L. Congenital histiocytosis X. Pediatr Radiol 23, 181–182 (1993). https://doi.org/10.1007/BF02013826
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DOI: https://doi.org/10.1007/BF02013826