Abstract
Tumors of smooth muscle origin are rare in childhood. We report a case of multiple bronchial leiomyomata in a seven year old girl with clinical HIV infection who presented with new onset of wheezing. Clinical details of this case have been published elsewhere, but without imaging studies [1].
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References
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Editorial commentary
In the past several years, scattered accounts of leiomyoma and/or leiomyosarcoma have been published in HIV infected pediatric patients who had prior LIP. The tumors have been noted in the liver, gastrointestinal tract but mostly in the lung, both in the trachea, bronchi and lung parenchyma.
The tumor cells are Desmin positive and, on light and electron microscopy, are felt to be of smooth muscle origin. They must be distinguished from the collections of spindle cells that seem to be a pseudotumor in HIV patients with mycobacterium avium intracellulare; the cases of this latter pseudotumor have been in the adult HIV literature.
W.E.Berdon (Managing Editor)
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Balsam, D., Segal, S. Two smooth muscle tumors in the airway of an HIV-infected child. Pediatr Radiol 22, 552–553 (1992). https://doi.org/10.1007/BF02013014
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DOI: https://doi.org/10.1007/BF02013014