Abstract
A cerebellar lesion was detected by ultrasonography (US) in a symptomatic newborn. Magnetic Resonance Imaging (MRI) demonstrated this lesion as a gyriform structure. Therefore a rare dysplastic gangliocytoma was suspected, which was compatible with histopathology. Immunohistochemical studies (monoclonal antibody Ki-67) showed signs of progression.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Lhermitte J, Duclos P (1920) Sur un ganglionerome diffus du cortex du cervelet. Bull Assoc Fr Etude Cancer 9: 99
Carter JE, Merren MD, Swann KW (1989) Preoperative diagnosis of Lhermitte-Duclos disease by magnetic resonance imaging: case report. J Neurosurg 70: 135
Sabin HI, Lidov HG, Kendall BE, Symon L (1988) Lhermitte-Duclos disease (dysplastic gangliocytoma): a case report with CT and MRI. Acta Neurochir (Wien) 93: 149
Brown WR, Angelo JN, Kelly DL (1980) Lhermitte-Duclos disease: case report with computerized tomographic scan. Neurosurgery 6: 189
Carbone F, Brihaye J, Drochmans P (1955) Spongioblastome pariétooccipital et gangliocytome du cervelet chez le même malade. Acta Neurol Psychiatr Belg 55: 568
Pritchett PS, Kind TI (1978) Dysplastic gangliocytoma of the cerebellum: an ultrastructural study. Acta Neuropathol (Berl) 41: 1
Reeder RF, Saunders RL, Roberts DW, Fratkin JD, Cromwell LD (1988) Magnetic resonance imaging in the diagnosis and treatment of Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum) Neurosurgery 23: 240
Reznik M, Schoenen J (1983) Lhermitte-Duclos disease. Acta Neuropathol (Berl) 59: 88
Beuche W, Wickboldt J, Friede RL (1983) Lhermitte-Duclos disease: its minimal lesions in electron microscope data and CT findings. Clin Neuropathol 2: 163
Roessmann U, Wongmongkolrit T (1984) Dysplastic gangliocytoma of cerebellum in a newborn: case report. J Neurosurg 60: 845
Heitkamp JW, Rose JE (1983) Neck pain following migration of a ventriculocervical shunt. Surg Neurol 19: 285
Probst A, Ulrich J, Zdrojewski B, Hirt HR (1979) Cerebellar ganglioglioma in a child. J Neuropathol Exp Neurol 38: 57
Romiev J, Montoya F, Frerebeau C (1976) Tumeur hamartomateuse du cervelet évoquant le syndrome de Lhermitte et Duclos. Pédiatrie 31: 627
Milbouw G, Born JD, Martin D, Collignon J, Hans P, Reznik M, Bonnal J (1988) Clinical and radiological aspects of dysplastic gangliocytoma (Lhermitte-Duclos disease): a report of two cases with review of the literature. Neurosurgery 22: 124
Ambler M, Pogacar S, Sidman R (1969) Lhermitte-Duclos disease (granule cell hypertrophy of the cerebellum): pathological analysis of the first familial cases. J Neuropathol Exp Neurol 28: 622
Marano SR, Johnson PC, Spetzler RF (1988) Recurrent Lhermitte-Duclos disease in a child: case report. J Neurosurg 69: 599
Lejeune JP, Blond S, Dupard T, Combelles G, Delandsheer JM (1987) Maladie de Lhermitte-Duclos: á propos d'une observation. Neurochirurgie 33: 408
Schröder R, Bien K (1991) Proliferative activity of pilocytic astrocytomas: examination using the monoclonal antibody Ki-67. Adv Neurosurg 19: 176
Altman NR (1988) MR and CT characteristics of gangliocytoma: a rare cause of epilepsy in children. AJNR 9: 917
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Dietlein, M., Schröder, R., Widemann, B. et al. Dysplastic gangliocytoma of cerebellum in a newborn. Pediatr Radiol 22, 131–133 (1992). https://doi.org/10.1007/BF02011314
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02011314