Summary
The morphometric analysis of the size of adenomatous prolactin cells shows that bromocriptine-induced cell skrinkage halts if treatment with the drug is discontinued for more than 2 days. Different cell components (nucleus, cytoplasm, nucleolus) do not react to treatment to the same extent.
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References
Flückiger, E., del Pozo, E., and Werder, K. von, Prolactin: Physiology, pharmacology, and clinical findings, p. 189. Springer, Berlin/Heidelberg/New York 1982.
Pawlikowski, M., Kunert-Radek, J., and Stepien, H., J. Endocr.79 (1978) 245.
Quadri, S. K., Lu, K. H., and Meites, J., Science176 (1972) 417.
Rengachari, S. S., Tomita, T., Jefferies, B. F., and Watanabe, I., Neurosurgery10 (1982) 242.
Landolt, A. M., Neurosurgery11 (1982) 395.
Landolt, A. M., Acta neurochir., suppl.25 (1975) 4.
Weibel, E. R., Kistler, G. S., and Scherle, F. W., J. Cell Biol.30 (1966) 23.
Maurer, R. A., J. biol. Chem.255 (1980) 8092.
Maurer, R. A., Nature294 (1981) 94.
Miller, Jr., O. L., Beatty, B. R., Hamkalo, B. A., and Thomas, Jr., C. A. Cold Spring Harb. Symp. quant. Biol.35 (1970) 505.
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Acknowledgments. We thank the EMDO Foundation, Zurich and the Sandoz-Foundation, Basel for financial support and Susan Eastwood-Berry, San Francisco for editorial assistance.
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Landolt, A.M., Minder, H., Osterwalder, V. et al. Bromocriptine reduces the size of cells in prolactin-secreting pituitary adenomas. Experientia 39, 625–626 (1983). https://doi.org/10.1007/BF01971131
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DOI: https://doi.org/10.1007/BF01971131