Zusammenfassung
Die systematische Fraktionierung eines Alkoholauszugs der FlechteCladonia leptoclada ergab, dassl-Usninsäure der hauptsächliche tumorhemmende Bestandteil ist.
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References
Tumor Inhibitors. 105. For previous paper in the series, seeC. H. Lantz, J. G. Kalpaxis, J. Larner, R. M. Schubert andS. M. Kupchan, Biochem. Pharmac., in press.
J. L. Hartwell, Lloydia34, 386 (1971).
Thalli ofCladonia leptoclada were collected in New Zealand in June, 1965. We thankDr. Robert E. Perdue Jr., U.S. Department of Agriculture, Beltsville, Md., for supplying the plant material.
Tumor-inhibitory activity was assayed under the auspices of the National Cancer Institute as described byR. I. Geran, N. H. Greenberg, M. M. McDonald, A. M. Schumacher andB. J. Abbott, Cancer Chemother. Rep. part 3,3, 1 (1972).
W. Karrer,Konstitution und Vorkommen der organischen Pflanzenstoffe (Birkhäuser Verlag, Basel 1958), p. 710.
S. Forsen, M. Nilsen andC. Wachtmeister, Acta chem. scand.16, 583 (1962).
K. Adachi, Japanese Patent, 73 16, 603; Chem. Abstr.80, 30695z (1974).
This work was supported by grants from the National Cancer Institute (No. CA-11718) and the American Cancer Society (No. CI-102-J), and a contract with the Division of Cancer Treatment, National Cancer Institute (No. N01-CM-12099).
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Morris Kupchan, S., Kopperman, H.L. l-Usnic acid: Tumor inhibitor isolated from lichens. Experientia 31, 625 (1975). https://doi.org/10.1007/BF01944592
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DOI: https://doi.org/10.1007/BF01944592