Abstract
The personal series of 30 cystic tumors of the pancreas [12 serous cystic tumors (SCT) and 18 mucinous cystic tumors (MCT)] is presented. All neoplasms were evaluated with ultrasonography (US) 28 of 30 with computed tomography (CT); the tumoral histotype could be correctly defined in 73% of cases (seven of 12 SCT and 15 of 18 MCT). Percutaneous fine-needle aspiration (FNA) with diagnostic aims (preparation of cytological smears and/or biochemical assays) was performed in only 10 of 30 cases, yielding a 100% sensitivity; on the whole, the combined use of imaging modalities and FNA allowed correct characterization of the cystic tumors in 27 of 30 cases (90%). The usefulness of a precise diagnostic workup of these neoplasms is emphasized, due to their prognostic and therapeutic outcome.
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Compagno J, Oertel JE: Microcystic adenomas of the pancreas (glycogen-rich cystadenomas).Am J Clin Pathol 69:289–298, 1978
Compagno J, Oertel JE: Mutinous cystic neoplasms of the pancreas with overt and latent malignancy (cystadenocarcinoma and cystadenoma).Am J Clin Pathol 69:573–580, 1978
Yamaguchi K, Enjoji M: Cystic neoplasms of the pancreas.Gastroenterology 92:1934–1943, 1987
Friedman AC, Lichtenstein JE, Dachman AH: Cystic neoplasms of the pancreas. Radiological-pathological correlation.Radiology 149:45–50, 1983
Itai Y, Moss AA, Ohtomo K: Computed tomography of cystadenoma and cystadenocarcinoma of the pancreas.Radiology 145:419–425, 1982
Itai Y, Ohhashi K, Furui S, Araki T, Murakami Y, Ohtomo K, Atomi Y: Microcystic adenoma of the pancreas: Spectrum of computed tomographic findings.JCAT 12:797–803, 1988
Johnson CD, Stephens DH, Charboneau JW, Carpenter HA, Welch TJ: Cystic pancreatic tumors: CT and sonographic assessment.AJR 151:1133–1138, 1988
Araki T, Ohtomo K, Itai Y, Iio M: Demonstration of septa in cystic lesions: Comparison study by computed tomography and ultrasound.Clin Radiol 33:325–329, 1982
Bastid C, Sahel J, Sastre B, Schurgers P, Sarles H: Mutinous cystadenocarcinoma of the pancreas. Ultrasonographic findings in 5 cases.Acta Radiol 30:45–47, 1989
Busilacchi P, Rizzatto G, Bazzocchi M, Boltro E, Candiani F, Ferrari F, Giuseppetti GM, Mirk P, Rubaltelli L, Volterrani L, Zappasodi F: Pancreatic cystadenocarcinoma: Diagnostic problems.Br J Radiol 55:558–561, 1982
Carroll B, Sample WF: Pancreatic cystadenocarcinoma: CT body scan and gray scale ultrasound appearance.AJR 131:339–341, 1978
De Santos LA, Bernardino ME, Paulus DD, Martin RE: Computed tomography of cystadenoma of the pancreas. Case report.JCAT 2:222–225, 1978
Eresue J, Drouillard J, Philippe JC, Guibert JL, Roux P, Tavernier J: CT and US findings in pancreatic ductal tumours. A report of an unusual case and review of the literature.Eur J Radiol 5:40–42, 1985
Fond A, Bret PM, Bretagnolle M, Thiesse P, Marion D, Dubreuil A, Labadie M: Ultrasound and percutaneous fine needle biopsy of cystic tumors of the pancreas.JBR-BTR 67:277–284, 1984
Freeny PC, Weinstein CJ, Taft DA, Allen FH: Cystic neoplasms of the pancreas: New angiographic and ultrasonographic findings.AJR 131:795–802, 1978
Herrera L, Glassman CI, Komins JI: Mucinous cystic neoplasm of the pancreas demonstrated by ultrasound and endoscopic retrograde pancreatography.Am J Gastroenterol 75:512–515, 1980
Lloyd TV, Antonmattei S, Freimanis AK: Gray scale sonography of cystadenoma of the pancreas: Report of two cases.J Clin Ultrasound 7:149–151, 1979
Maraist DV, Sibille PJ: Cystadenoma of the pancreas demonstrated by computed tomography with the acta-scanner. A case report.Comput Tomogr 1:121–124, 1977
Panuel M, Devred P, Delarue A, Faure F, Grangier ML, Padovani J: Cystadénome multiloculaire du pancréas. Une tumeur exceptionelle chez l'enfant.J Radiol 65:275–278, 1984
Parienty RA, Ducellier R, Lubrano JM, Picard JD, Pradel J, Smolarski N: Cystadenomas of the pancreas: Diagnosis by computed tomography.JCAT 4:364–367, 1980
Vilgrain V, Menu Y, Lorphelin JM, Nahum H: Cystadénomes pancréatiques. Piéges et limites du diagnostic radiologique.J Radiol 68:455–463, 1987
Warshaw AL, Rutledge PL: Cystic tumors mistaken for pancreatic pseudocysts.Ann Surg 205:393–398, 1987
Wolfman NT, Ramquist NA, Karstaedt N, Hopkins MB: Cystic neoplasms of the pancreas: CT and sonography.AJR 755:37–41, 1982
Wolson AH, Walls WJ: Ultrasonic characteristics of cystadenoma of the pancreas.Radiology 119:203–205, 1976
Zirinsky K, Abiri M, Baer JW: Computed tomography demonstration of the pancreatic microcystic adenoma.Am J Gastroenterol 79:139–142, 1984
Rossi A, Ferrozzi F, Maccarini PA, Rossi G, Tagliaferri B, Rossi L: Neoplasie cistiche pancreatiche. Aspetti eco-Tc e diagnostica differenziale.Radiol Med 76:425–433, 1988
Turnage RH, Eckhauser FE, Vinik AI, Strodel WE, Thompson NW, Smid A, Smid D: Diagnostic dilemmas in patients with cystic neoplasms of the pancreas.Int J Panereatol 3:477–490, 1988
Mathieu D, Guigui B, Valette PJ, Dao T, Bruneton JN, Bruel JH, Pringot J, Vasile N: Pancreatic cystic neoplasms.Radiol Clin North Am 27:163–176, 1989
Didolkar MS, Malhotra Y, Holyoke ED, Elias EG: Cystadenoma of the pancreas.Surg Gynecol Obstet 140:925–928, 1975
Clark LR, Jaffe MH, Choyke PL, Grant EG, Zeman RK: Pancreatic imaging.Radiol Clin North Am 25:489–501, 1985
Friedman AC, Lichtenstein JE, Fishman EK, Oertel JE, Dachman AH, Siegelman SS: Solid and papillary epithelial neoplasm of the pancreas.Radiology 154:333–337, 1985
Fugazzola C, Portuese A, Bergamo Andreis IA, Delia Sala S, Cinquino M, De Iorio M, Artico L, Loreti S: Ecotomografia del pancreas. In: Ziviello M, et al. (eds):Ecotomografia. Napoli: Idelson, 1986, pp 151–186
Jones EC, Suen KC, Grant DR, Chan NH: Fine-needle aspiration cytology of neoplastic cysts of the pancreas.Diagn Cytopathol 3:238–243, 1987
Schwerk WB: Ultrasonically guided percutaneous puncture and analysis of aspirated material of cystic pancreatic lesions.Digestion 21:184–192, 1981
Laing FC, Gooding GAW, Brown T, Leopold GR: Atypical pseudocysts of the pancreas: An ultrasonographic evaluation.J Clin Ultrasound 7:27–33, 1979
Procacci C, Portuese A, Fugazzola C, Pederzoli P, Caudana R, Gallo E, Bergamo Andreis IA, Spiller M, Zonta L, Graziani R, Tinazzi Martini P: Duodenal duplication in the adult: Its relationship with pancreatitis.Gastrointest Radiol 13:315–322, 1988
Kaplan JO, Isikoff MB, Barkin J, Livingstone AS: Necrotic carcinoma of the pancreas: The pseudo-pseudocyst.JCAT 4:166–167, 1980
Freeny PC, Lawson TL: Rare pancreatic neoplasms. In: Freeny PC, Lawson TL (eds):Radiology of the Pancreas. Berlin, Heidelberg, New York: Springer Verlag, 1982, pp 580–582
Frija J, Schmit P, Vadrot D, Katz M, Laval-Jeantet M: Non-secreting islet cell adenoma of the pancreas, evaluated by computed tomography and sonography. Report of a case.Eur J Radiol 2:160–161, 1982
Fugazzola C, Procacci C, Bergamo Andreis IA, Iacono C, Portuese A, Mansueto GC, Residori E, Zampieri P, Jannucci A, Serio G: The contribution of ultrasonography and computed tomography in the diagnosis of nonfunctioning islet cell tumors of the pancreas.Gastrointest Radiol 15:139–144, 1990
Choi BI, Kim KW, Han MC, Kim YI, Kim CW: Solid and papillary epithelial neoplasms of the pancreas: CT findings.Radiology 166:413–416, 1988
Vellet D, Leiman G, Mair S, Bilchick A: Fine-needle aspiration cytology of mucinous cystadenocarcinoma of the pancreas. Further observations.Acta Cytol 32:43–48, 1988
Pinto MM, Avila NA, Criscuolo EM: Fine needle aspiration of the pancreas. A five-year experience.Acta Cytol 32:39–42, 1988
Kimura K, Yamanaka T, Sakai H, Ido K, Seki H, Yoshida Y: Biochemical and cytological analyses of cystic fluid aspirated by percutaneous puncture under ultrasonic guidance in cystic diseases of the pancreas.Gastroenterol Jpn 17:4–9, 1982
Nishida K, Shiga K, Kato K, Kunihiro K, Fujii T, Tomii T, Yamamoto H, Yamane E, Nishioka B, Yoshikawa T, Kondo M: Two cases of pancreatic cystadenocarcinoma with elevated CA 19-9 levels in the cystic fluid in comparison with two cases of pancreatic cystadenoma.Hepatogastroenterology 36:442–445, 1989
Yanagisawa A, Katoh Y, Sugano H, Ohhashi K, Takekoshi T, Takagi K: Classification of the pancreatic cyst with atypical epithelium.Biliary Tract Pancreas 5:1079–1085, 1984
Itai Y, Ohhashi K, Nagai H, Murakami Y, Kokubo T, Makita K, Ohtomo K: “Ductectatic” mucinous cystadenoma and cystadenocarcinoma of the pancreas.Radiology 161:697–700, 1986
Pressman BD, Asch T, Casarella WJ: Cystadenoma of the pancreas. A reappraisal of angiographic findings.AJR 119:115–120, 1973
Uflacker R, Amaral NM, Lima S, Aakhus T, Pereira E, Kuroda K: Angiography in cystadenoma and cystadenocarcinoma of the pancreas.Acta Radiol Diagn 27:189–195, 1980
Minami M, Itai Y, Ohtomo K, Yoshida H, Yoshikawa K, Iio M: Cystic neoplasms of the pancreas: Comparison of MR imaging with CT.Radiology 171:53–56, 1989
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Fugazzola, C., Procacci, C., Andreis, I.A.B. et al. Cystic tumors of the pancreas: Evaluation by ultrasonography and computed tomography. Gastrointest Radiol 16, 53–61 (1991). https://doi.org/10.1007/BF01887305
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DOI: https://doi.org/10.1007/BF01887305