Summary
The study provides information on the epidemiology of HTLV-III infection and the lymphadenopathy syndrome (LAP) in 374 German homosexual men. Sexual contacts in the USA and rectal enemas before receptive anal intercourse are the main risk factors associated with virus transmission. HTLV-III seropositivity is significantly correlated with LAP. Prominent clinical signs are infreqquent. Immunological and haematological abnormalities are prevalent, and the retrovirus infection is frequently associated with serological markers of other viruses (hepatitis B, herpes group viruses). Lymphadenopathy as a manifestation of HTLV-III infection is discussed within the context of AIDS-related disorders.
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Abbreviations
- AIDS:
-
Acquired Immunodeficiency Syndrome
- CMV:
-
Cytomegalovirus
- EBV:
-
Epstein-Barr virus
- HBV:
-
Hepatitis B virus
- HTLV-III:
-
Human leukaemia retrovirus type III
- LAP:
-
Lymphadenopathy
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Bienzle, U., Guggenmoos-Holzmann, I., Zwingenberger, K. et al. Lymphadenopathy and antibodies to HTLV-III in homosexual men. Klin Wochenschr 63, 597–602 (1985). https://doi.org/10.1007/BF01733012
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DOI: https://doi.org/10.1007/BF01733012