Abstract
This paper reviews the literature regarding the development of gastric cancer in the stomach remnant following gastric resection. Although there is as yet little supporting experimental evidence, clinical studies suggest that the risk of developing gastric cancer is increased, perhaps as much as 6-fold, following partial gastrectomy for benign lesions. It also appears that the risk of developing cancer is greatest if the lesion for which the gastrectomy was originally performed was a gastric ulcer rather than a duodenal ulcer. The type of gastrectomy does not seem to influence this increased risk. Hypotheses are reviewed concerning the role of changes in gastric morphology following partial gastrectomy in the development of cancer.
Résumé
Revue de la littérature concernant le développement d'un cancer dans le moignon gastrique après gastrectomie subtotale. Malgré l'absence de preuve expérimentale, les études cliniques suggèrent que le risque d'apparition d'un cancer est accru, peutêtre jusqu'à 6 fois, après gastrectomie pour lésion bénigne. Le risque semble être également plus élevé après gastrectomie pour ulcère gastrique que pour ulcère duodénal. Le type de résection gastrique n'a aucune influence. Diverses hypothèses ont été émises concernant les altérations postopératoires de la morphologie gastrique et leur rôle possible dans le développement du cancer: ces hypothèses sont revues.
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Freeman, M.A., Berne, C.J.: Gastric carcinoma of gastrojejunal stoma. Gastroenterology27:210, 1954
Peters, H., Schubert, H.J., Reifferscheid, M.: Das carcinoma in Restmagen nach Resektion wegen gutartiger Befunde. Langenbecks Arch. Chir.336:219, 1974
Reynolds, K.W., Johnson, A.G., Fox, B.: Is intestinal metaplasia of the gastric mucosa a pre-malignant lesion? Clin. Oncol.1:101, 1975
Lawson, H.H.: Effect of duodenal contents on the gastric mucosa. S. Afr. J. Surg.3:79, 1965
Gough, D.C., Craven, J.L.: Presentation to British Society of Gastro-enterology. Gut16:843, 1975
Nicholls, J.C.: Carcinoma of the stomach following partial gastrectomy for benign gastroduodenal lesions. Br. J. Surg.61:244, 1974
Swynnerton, B.F.A., Tanner, N.C.: Chronic gastric ulcer—a comparison between a gastroscopically controlled series treated medically and a series treated by surgery. Br. Med. J.2:841, 1953
Helsingen, N., Hillestad, L.: Cancer development in the gastric stump after partial gastrectomy for ulcer. Ann. Surg.143:173, 1956
Taksdal, S., Stalsberg, H.: Histology of gastric carcinoma occurring after gastric surgery for benign conditions. Cancer32:162, 1973
Morgenstern, L., Vamakawa, T., Seltzer, D.: Carcinoma of the gastric stump. Am. J. Surg.125:29, 1973
Saegesser, F., James, D.: Cancer of the gastric stump after partial gastrectomy for ulcer (Billroth II principle) for ulcer. Cancer29:1150, 1972
Hofstetter, J.R., Realini, S., Fasel, J., Arnold, J., Saegesser, F.: Cancer du magnon gastrique après resection pour ulcère bénin. Praxis64:1472, 1975
Debray, V.C., Bouvry, M., Roches, P.: Stump carcinoma after gastric resection for ulcer. Schweiz. Med. Wochenschr.88:631, 1958
De Jode, L.R.: Gastric carcinoma following gastroenterostomy and partial gastrectomy. Br. J. Surg.48:512, 1961
Doll, R., Avery-Jones, F., Buchatzsch, M.M.: Special report to Ser. Med. Res. Council, London. No. 276, 1951
Hilbe, G., Salzer, G.M., Hussl, H., Kutschera, H.: The incidence of cancer in the gastric remnant after subtotal gastric resection. Arch. Klin. Chir.323:142, 1968
Stalsberg, H.: Stomach cancer and previous gastric surgery. Gastroenterology62:1276, 1972
Stalsberg, H.: Stomach cancer following gastric surgery for benign conditions. Lancet2:1175, 1971
Skinner, J.M., Heenan, P.J., Whitehead, R.: Atrophic gastritis in gastrectomy specimens. Br. J. Surg.62:23, 1975
Duplessis, D.J.: The distribution of gastritis in carcinoma of the stomach. Br. J. Surg.61:521, 1974
Lagache, G., Vankemmel, M.: Cancer of the gastric stump following gastrectomy for ulcer. Arch. Chir.20:618, 1966
Montgomery, R.D., Richardson, B.P.: Gastric ulcer and cancer. Q. J. Med.44:591, 1975
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Nicholls, J.C. Stump cancer following gastric surgery. World J. Surg. 3, 731–734 (1979). https://doi.org/10.1007/BF01654802
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DOI: https://doi.org/10.1007/BF01654802