Abstract
The transsphenoidal approach to the pituitary gland is emerging as the safest and most efficacious procedure for the management of pituitary tumors. With the aid of the microscope large tumors producing visual symptoms can be removed and microadenomata producing only signs and symptoms of endocrinopathies can be safely and adequately approached. The procedure is described in this report. The results of its use in 29 patients with selected illustrative case reports are described.
Résumé
L'approche trans-sphénoidale dans la chirurgie de l'hypophyse est en voie de devenir la technique de choix dans le traitement des tumeurs hypophysaires. L'emploi du microscope permet d'exciser non seulement les tumeurs volumineuses responsables de symptÔmes visuels mais aussi les microadénomes manifestés uniquement par des syndrÔmes endocrinologiques et ceci adéquatement et sans risque. L'article décrit la technique et rapporte les résultats obtenus chez 29 patients en plus de présenter en détails quelques cas choisis pour leur représentativité.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Krause, F.: Hirnchirugie (Freilegungder Hypophyse). Dtsch. Klin.8:1004, 1905
Halstead, A.E.: Remarks on the operative treatment of tumors of the hypophysis: Report on two cases operated on by an oronasal method. Surg. Gynecol. Obstet.10:494, 1910
Cushing, H.: Surgical experiences with pituitary disorders. J.A.M.A.63:1515, 1914
Gulot, G.: Adenomes Hypophysaires. Paris, Masson, 1958
Hardy, J., Wigser, S.M.: Trans-sphenoidal surgery of pituitary fossa tumors with televised radiofluoroscopic control. J. Neurosurg.23:612, 1965
Hardy, J., Ciric, I.S.: Selective anterior hypophysectomy in the treatment of diabetic retinopathy: a transsphenoidal microsurgical technique. J.A.M.A.203 (2), 95, 1968
Olson, D.R., Guiot, G., Dermone, P.: The symptomatic empty sella: prevention and correction via the transsphenoidal approach. J. Neurosurg.37:533, 1972
Samaan, N.A., Leavens, M.E., Jesse, R.J., Jr.: Pituitary tumors: recent advances in diagnosis and management. Tex. Med.70:55, 1974
Bohmer, T., Berdal, P., Hangen, H.N.: Transphenoidal subtotal hypophysectomy in the treatment of acromegaly. Acta Endocrinol.77:477, 1974
Ciric, I.S., Tarkington, J.: Transsphenoidal microsurgery. Surg. Neurol.2(3):207, 1974
Dalton, G.: Transsphenoidal hypophysectomy for pituitary tumors. Proc. R. Soc. Med.67:885, 1974
Guiot, G., Thibaut, B.: L'extirpation des adenomes hypophysaires par voie transsphenoidale. Neurochirurgie1:133, 1959
Williams, R.A.: Transsphenoidal hypophysectomy for acromegaly. Proc. Soc. Med.67:881, 1974
Nasr, H., Mozaffarian, G., Pensky, J., Pearson, O.H.: Prolactin secreting pituitary tumors in women. J. Clin. Endocrinol. Metab.35:505, 1972
Pearson, O.H., Brodkey, J.S., Kaufman, B.: Endocrine evaluation and indications for surgery of functional pituitary adenomas. Clin. Neurosurg.21:26, 1974
Forbes, A.P., Henneman, P.H., Griswold, G.C., Albright, F.: Syndrome characterized by galactorrhea, amenorrhea, and low urinary FSH: comparison with acromegaly and normal lactation. J. Clin. Endocrinol. Metab.14:265, 1954
Lawrence, J.H., Tobias, C.A., Linfoot, J.A., Boen, J.L., Chong, C.Y.: Heavy particle therapy in acromegaly and Cushing disease. J.A.M.A.235:2307, 1976
Nelson, D.H., Meakin, J.W., Thorn, G.W.: ACTH producing pituitary tumors following adrenalectomy for Cushing's syndrome. Ann. Intern. Med.52:560, 1960
Author information
Authors and Affiliations
Additional information
Doctor Nielson is sponsored by the U. S. Navy. The opinions expressed are those of the authors and in no way reflect the official view of the Bureau of Medicine and Surgery of the Navy or of the United States Naval service at large.
Rights and permissions
About this article
Cite this article
Nielson, K.D., Watts, C. & Clark, K. Transsphenoidal microsurgery for selective removal of functional pituitary microadenomas. World J. Surg. 1, 79–84 (1977). https://doi.org/10.1007/BF01654738
Issue Date:
DOI: https://doi.org/10.1007/BF01654738