Summary
An algae screening program, including cultured macroalgae, cultured cyanobacteria and cultured eukaryotic microalgae has been undertaken. Methods for the isolation, purification, preservation and cultivation of axenic cyanobacteria and eukaryotic cultures have been developed. Screening of these groups for biologically active components has lead to the isolation of pachydictyol and caulerpenyne from cultured macroalgae, while a series of hapalindoles and an antifungal depsipeptide have been isolated from cyanobacteria.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Amico, V., G. Oriente, M. Piatelli, C. Tringali, E. Fattorusso, S. Magno and L. Mayol. 1978. Caulerpenyne, and unusual sesquiterpenoid from the green algaCaulerpa prolifera. Tetrahedron Lett. 3593–3596.
Gorham, P.R. and W.W. Carmichael. 1979. Phycotoxins from blue-green algae. Pure Appl. Chem. 52: 165–174.
Hirschfeld, D.R., W. Fenical, G.H.Y. Lin, R.M. Wing, P. Radlick and J.J. Sims. 1973. Marine natural products. VIII. Pachydictyol A, an exceptional diterpene from the brown alga,Pachycityon coriaceum. J. Am. Chem. Soc. 95: 4049–4050.
Irvine, D.E.G. and D.M. John (ed.). 1984. Systematics of the green algae. Academic Press, New York, New York.
McLachlan, J. 1973. Growth media-marine. In: (Stein, J.R., ed.), Handbook of Phycological Methods, pp. 25–51, Cambridge University Press, New York.
Moore, R.E. 1977. Toxins from blue-green algae. Bioscience. 27: 797–802.
Moore, R.E., C. Cheuk, X.G. Yang, G.M.L. Patterson, R. Bonjouklian, T.A. Smitka, J.S. Mynderse, R.S. Foster, N.D. Jones, J.K. Swartzendruber and J.B. Deeter. 1987. Hapalindoles, antibacterial and antimycotic alkaloids from the cyanophyteHapalosiphon fontinalis. J. Org. Chem. 52: 1036–1043.
Moore, R.E. and G.M.L. Patterson. 1985. Hapalindoles. Eur. Patent 0 171 283 A2.
Provasoli, L. 1963. Growing marine seaweeds. Proc. Intern. Seaweed Symp. 4: 9–17. Pergamon Press. New York.
Provasoli, L. 1968. Media and prospects for the cultivation of marine algae. In: (A. Watanabe and A. Hattori, eds.), Cultures and collections of algae. Proc. U.S. — Japan Conf. Hakone. Sept. 1966. Jap. Soc. Pl. Physiol., pp. 63–75.
Rippka, R., J. Deruelles, J.B. Waterbury, M. Herdman and R.Y. Stanier. 1979. Generic assignments, strain histories and properties of pure cultures of cyanobacteria. J. Gen. Microbiol. 111: 1–61.
Rippka, R., J.B. Waterbury and R.Y. Stanier. 1981. Isolation and purification of cyanobacteria: some general principles. In: The prokaryotes: a handbook on habitats, isolation and identification of bacteria (M.P. Starr, H. Stolp, H.G. Truper, A. Balows and H.G. Schlegel, eds.), pp. 212–220, Springer-Verlag, New York.
Round, F.E. 1981. In. The ecology of algae. Cambridge University Press, New York.
Schwartz, R.E., C.F. Hirsch, J.P. Springer, D.J. Pettibone and D.L. Zink. 1987. Unusual cyclopropane-containing hapalindolinones from a cultured cyanobacteria. J. Org. Chem. 52: 3704–3706.
Shimizu, Y. 1978. Dinoflagellate toxins. In: Marine natural products, chemical and biological perspectives, Vol. I (Scheuer, P.J. ed.), pp. 1–42.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Schwartz, R.E., Hirsch, C.F., Sesin, D.F. et al. Pharmaceuticals from cultured algae. Journal of Industrial Microbiology 5, 113–123 (1990). https://doi.org/10.1007/BF01573860
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01573860