Summary
Interferon (IF) induction and antiviral activity by purified spherical (S) or filamentous (F) virus-like particles and S-derived RNA was studied. A single administration of S particles prior to virus challenge reduced significantly the mortality of mice infected with western equine encephalitis (WEE) virus.
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Takehara, M., Kuida, K. & Mori, K. Antiviral activity of virus-like particles fromLentinus edodes (Shiitake). Archives of Virology 59, 269–274 (1979). https://doi.org/10.1007/BF01317423
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DOI: https://doi.org/10.1007/BF01317423