Summary
Ileoanal anastomosis is a surgical procedure performed in patients with ulcerative colitis. In a small number of patients operated on for ulcerative colitis, Crohn's disease occurs in the reservoir, mimicking pouchitis, and may lead to pouch excision and to a permanent terminal ileostomy. Two patients with recurrent Crohn's disease in the reservoir after ileoanal anastomosis were treated with azathioprine for 18 and 24 months, respectively. Azathioprine induced a complete clinical and endoscopic remission. These two observations suggested that immunosuppressive drugs were a good option for permanent ileostomy in cases of recurrence of Crohn's disease in the reservoir after ileoanal anastomosis.
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Berrebi, W., Chaussade, S., Bruhl, A.L. et al. Treatment of Crohn's disease recurrence after ileoanal anastomosis by azathioprine. Digest Dis Sci 38, 1558–1560 (1993). https://doi.org/10.1007/BF01308621
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DOI: https://doi.org/10.1007/BF01308621