Abstract
Gastrointestinal bleeding has been observed in long-distance runners. We prospectively studied participants of the Eighth Annual Marine Corps Marathon to determine the incidence of gastrointestinal blood loss associated with long-distance running. Of 600 runners contacted, 125 (21%) returned a questionnaire as well as pre- and postmarathon stool specimens. Stool specimens converted from Hemoccult negative to positive in 29/125 (23%) of the participants, indicating that running the marathon was associated with gastrointestinal blood loss (P<0.001). The incidence of this conversion (negative to positive) was significant for both males (N=68,P<0.001) and females (N=57,P<0.05). Gastrointestinal bleeding appeared to be independent of age, race time, abdominal symptoms, and the recent ingestion of aspirin, vitamin C, or steak.
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Olsen E: Happy anniversary: Running boom. Runner 4:20–49, 1982
Costill DL: Physiology of marathon running. JAMA 221:1024–1029, 1972
Schiff HB, MacSearraigh ET, Kallmeyer JC: Myoglobinuria, rhabdomyolysis and marathon running. Q J Med 47:463–372, 1978
Anonymous: The haematuria of the long-distance runner. Br Med J 1:159, 1979 (editorial)
Heide T: The haematuria of the long-distance runner. Br Med J 2:547, 1979 (editorial)
Fred HL, Natelson EA: Grossly bloody urine of runners. South Med J 70:1394–1396, 1977
Scheuer J, Tipton CM: Cardiovascular adaptations to physical training. Annu Rev Physiol 39:221–251, 1977
Gibbons LW, Cooper KH, Martin RP, Pollock ML: Medical examination and electrocardiographic analysis of elite distance runners. Ann NY Acad Sci 301:283–296, 1977
Nicholl JP, Williams BT: Popular marathons: forecasting casualties. Br Med J 285:1464–1465, 1982
Fogoros RN: “Runners' trots”—Gastrointestinal disturbances in runners. JAMA 243(17):1743–1744, 1980
Sullivan SN: The gastrointestinal symptoms of running. N Engl J Med 304(15):915, 1981 (letter)
Cantwell JD: Gastrointestinal disorders in runners. JAMA 246(13):1404–1405, 1981
McMahon LF, Ryan MJ, Larson DL, Fisher RL: Occult gastrointestinal blood loss in marathon runners. Ann Intern Med 100:846–847, 1984
Stewart JG, Ahlquist DA, McGill DB, Ilstrup DM, Schwartz SS, Owen RA: Gastrointestinal blood loss and anemia in runners. Ann Intern Med 100:843–845, 1984
Stroehlein JR, Fairbands VF, McGill DB, Go VLW: Hemoccult detection of fecal occult blood quantitated by radioassay. Dig Dis Sci 21(10):841–844, 1976
Morris Dw, Hansell JR, Ostrow JD, Lee CS: Reliability of chemical tests for fecal occult blood in hospitalized patients. Dig Dis Sci 21(10):845–852, 1976
Clausen JP, Klausen K, Rasmussen B, Trap-Jenson J: Central and peripheral circulatory changes after training of the arms or legs. Am J Physiol 225:675–682, 1973
Grimby G: Renal clearances during prolonged supine exercise at different loads. J Appl Physiol 20:1294–1298, 1965
Rowell LB: Human cardiovascular adjustments to exercise and thermal stress. Physiol Rev 54:75–159, 1974
Rowell LB, Blackmon JR, Bruce RA: Indocyanine green clearance and estimated hepatic blood flow during mild to maximal exercise in upright man. J Clin Invest 43:1677–1690, 1964
Blacklock NJ: Bladder trauma in the long-distance runner: “10,000 metres haematuria.” Br J Urol 49:129–132, 1977
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The opinions and assertions contained herein are the private views of the authors and are not to be construed as official policy or as reflecting the views of the Department of the Army or the Department of Defense.
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McCabe, M.E., Peura, D.A., Kadakia, S.C. et al. Gastrointestinal blood loss associated with running a marathon. Digest Dis Sci 31, 1229–1232 (1986). https://doi.org/10.1007/BF01296525
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DOI: https://doi.org/10.1007/BF01296525