Abstract
To elucidate sleep disturbances in the etiology of peptic ulcers, the prevalence of peptic ulcer disease was compared among shift workers and daytime workers. The subjects (N=11,657) were employees of various institutions, such as factories, banks, or schools, and had undergone a mass x-ray examination of the upper gastrointestinal tract. With present shift workers (N=2269), the prevalence of gastric ulcers was 2.38% (N=54) and that of duodenal ulcers, 1.37% (N=31). With the past shift workers (N=2111), the prevalence of gastric ulcers was 1.52% (N=32) and that of duodenal ulcers, 0.62% (N=13). On the contrary, with the daytime workers (N=6525) the prevalence of gastric ulcer was 1.03% (N=67) and that of duodenal ulcer, 0.69% (N=45). The working schedule for 752 examinees was unknown. The prevalence of gastric and duodenal ulcers was higher with shift workers than daytime workers. Thus, shift work involving sleep disturbances may play an important role in the development of peptic ulcers.
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Boyd EJS, Wormsley KG: Etiology and pathogenesis of peptic ulcer.In Gastroenterology 4th ed., JE Berk (ed). Philadelphia, WB Saunders, 1985, pp 1013–1059
Segawa K, Mabuchi C, Shiozawa Z, Nakazawa S: The nocturnal intragastric pH in EEG sleep stages in peptic ulcer patients. Gastroenterol Jpn 12:1–6, 1977
Stacher G, Presslich B, Starker H: Gastric acid secretion and sleep stages during natural night sleep. Gastroenterology 68:1449–1455, 1975
Machida T: A study of intragastric pH in patients with peptic ulcer—with special reference to the clinical significance of basal pH value. Gastroenterol Jpn 16:447–458, 1981
Nakazawa S, Segawa K, Tsukamoto Y, Okada M: The disturbance of sleeping habit in peptic ulcer. Jpn J Psychosom Med 22:324–328, 1982
Kurata JH, Haile BM: Epidemiology of peptic ulcer disease. Clin Gastroenterol 13:289–307, 1984
Koller M: Health risks related to shift work. Int Arch Occup Environ Health 53:59–75, 1983
Aanonsen A: Medical problems of shift work. Ind Med Surg 28:422–427, 1959
Akerstedt T, Torvsall L, Gilberg M: Sleepiness and shift work: Field studies. Sleep 5:s95-s106, 1982
Akerstedt T: Work schedules and sleep. Experientia 40:417–422, 1984
Vrancianu R, Filcesu V, Inosecus V, Groza P, Persson J, Kadefors R, Peterson I: The influence of day and night work on the circadian variations of cardiovascular performance. Eur J Appl Physiol 48:11–23, 1982
Rutenfranz J, Colquhoun WP, Knauth P, Ghata JN: Biomedical and psychosocial aspects of shift work. Scand J Work Environ Health 3:165–182, 1977
Thiis-Evensen E: Shift work and health. Ind Med Surg 27:493–497, 1958
Kogi K: Effect of industrialization on working schedules. J Hum Ergol 5:133–143, 1976
Monroe LJ: Psychological physiological differences between good sleepers and poor sleepers. J Abnorm Psychol 72:255–264, 1967
Rutenfranz J, Knauth P: Hours of work and shift. Ergonomics 19:331–340, 1976
Taylor PJ: The problems of shift. J R Coll Physicians London 3:370–384, 1969
Johnson RL, Washeim H: Studies in gastric secretion. II. Gastric secretion in sleep. Am J Physiol 70:247–253, 1924
Levin E, Kirsner JB, Palmer WL, Butler C: The variability and periodicity of the nocturnal gastric secretion in normal individuals. Gastroenterology 10:939–951, 1948
Orr WC, Robinson MG: The sleeping gut. Med Clin North Am 65:1359–1376, 1981
McCallum RW, Berkowitz DM, Lerner E: Gastric emptying in patients with gastroesophageal reflux. Gastroenterology 80:285–291, 1981
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Segawa, K., Nakazawa, S., Tsukamoto, Y. et al. Peptic ulcer is prevalent among shift workers. Digest Dis Sci 32, 449–453 (1987). https://doi.org/10.1007/BF01296025
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DOI: https://doi.org/10.1007/BF01296025