Abstract
Recent studies indicate that lower esophageal sphincter pressure is influenced by manometric assembly diameter. This study determines the effect of assembly diameter on both esophageal sphincter pressure and peristaltic pressure in the esophageal body. We performed esophageal manometric studies in 6 normal subjects using graded assembly diameters. High-fidelity recording was achieved by using a noncompliant catheter-infusion system. The results indicate that increases in assembly diameter cause significant increases in peristaltic pressure amplitudes and in resting sphincter pressure in both the smooth and striated muscle portions of the esophagus. This phenomenon is best explained by the length-tension characteristics of esophageal muscle, increased stretch causing greater contraction force.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Biancani P, Spiro HM, Bejar J: Pressure-diameter characteristics of competent and incompetent human lower esophageal sphincter (LES). Gastroenterology 64:698, 1973
Biancani P, Zabinski MP, Bejar J, Spiro HM: Morphology and competence of the lower esophageal sphincter. Gastroenterology 64:699, 1973
Biancani P, Goyal RK, Phillips A, Spiro HM: Mechanics of sphincter action. Studies on the lower esophageal sphincter. J Clin Invest 52:2973–2978, 1973
Kaye MD, Showalter JP: Measurement of pressure in the lower esophageal sphincter. The influence of catheter diameter. Am J Dig Dis 19:860–863, 1974
Dodds WJ, Stef JJ, Arndorfer RC, Linehan JH, Hogan WJ: Improved infusion system for esophageal manometry. Clin Res 22:602, 1974
Stef JJ, Dodds WJ, Hogan WJ, Linehan JH, Stewart ET: Intraluminal esophageal manometry: an analysis of variables affecting recording fidelity of peristaltic pressures. Gastroenterology 67:221–230, 1974
Dodds WJ, Hogan WJ, Miller WN, Barreras RF, Arndorfer RC, Stef JJ: Relationship between serum gastrin concentration and loweresophageal sphincter pressure. Am J Dig Dis 20:201–207
Dodds WJ, Hogan WJ, Stef JJ, Miller WN, Lydon SB, Arndorfer RC: A rapid pull-through technique for measuring lower esophageal sphincter pressure. Gastroenterology 68:437–443, 1975
Dodds WJ, Hogan WJ, Reid DP, Stewart ET, Arndorfer RC: A comparison between primary esophageal peristalsis following wet and dry swallows. J Appl Physiol 35:851–857, 1973
Harris LD, Pope CE II: “Squeeze” vs. resistance: An evaluation of mechanism of sphincter competence. J Clin Invest 43:2272–2278, 1964
Cohen S, Green F: The mechanics of esophageal muscle contraction. Evidence of an inotropic effect of gastrin. J Clin Invest 52:2029–2040. 1973
Christensen J, Conklin JL, Freeman BW: Physiologic specialization at esophagogastric junction in three species. Am J Physiol 225:1265–1270, 1973
Author information
Authors and Affiliations
Additional information
This work was supported in part by USPHS Research Grant 1 R01 AM 15540.
Rights and permissions
About this article
Cite this article
Lydon, S.B., Dodds, W.J., Hogan, W.J. et al. The effect of manometric assembly diameter on intraluminal esophageal pressure recording. Digest Dis Sci 20, 968–970 (1975). https://doi.org/10.1007/BF01070885
Issue Date:
DOI: https://doi.org/10.1007/BF01070885