Conclusions
Veng-Pedersen and Modi have begun some very interesting investigations. The neural net technique as applied to pharmacodynamics appears to be a promising area of research. However, the results are far from conclusive at present. I believe it is too early to state that the neural net techniques will supplant the more traditional modeling techniques, particularly for short-term goals. Moreover, I hope that the former do notcompletely replace the latter, as the latter are what ultimately lead to the insights which are the main event in scientific discovery and progress.
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Siegel, R.A. Commentary on “neural networks in pharmacodynamic modeling. Is current modeling practice of complex kinetic systems at a dead end?”. Journal of Pharmacokinetics and Biopharmaceutics 20, 413–416 (1992). https://doi.org/10.1007/BF01062466
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DOI: https://doi.org/10.1007/BF01062466