Summary
A new apparatus with a capacity up to 24 kg per hour for physical entrapment of cell fragments or whole cells in polymeric networks was constructed, based on a high speed rotating nozzle-ring. Immobilized biocatalysts are prepared at laboratory scale with bead size under 1 mm diameter, with a deviation of 10 % or less in size distribution.
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Matulovic, U., Rasch, D. & Wagne, F. New equipment for the scaled up production of small spherical biocatalysts. Biotechnol Lett 8, 485–490 (1986). https://doi.org/10.1007/BF01025206
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DOI: https://doi.org/10.1007/BF01025206