Summary
Cyclosporin A and C are new antifungal antibiotics fromTrichoderma polysporum (Link ex Pers.) Rifai. The metabolites are produced in submerged culture and are extracted therefrom by organic solvents. Cyclosporin A is a nonpolar cyclic peptide with a molecular weight of 1202.6. The cyclosporins exhibit a narrow spectrum of antifungal activity and in addition have immunosuppressive properties.
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References
Arx von,J.A. (1970). The genera of fungi sporulating in pure culture. Lehre: J. Cramer
Bartnicki-Garcia,S. (1968). Ann. Rev. Microbiol.22, 87–108
Bartnicki-Garcia,S., Lippmann,E. (1972). J. Gen. Microbiol.71, 301–309
Bigger,C.H., White,M.H., Braymer,H.D. (1972). J. Gen. Microbiol.71, 159–166
Borel,J.F., Feurer,C., Gubler,H.U., Stähelin,H. (1976). Agents and Actions6, 432–440
Rifai,M.A. (1969). A revision of the genus Trichoderma. Mycol.Pap.116
Rüegger,A., Kuhn,M., Lichti,H., Loosli,H.R., Huguenin,R., Quiquerez,C., von Wartburg,A. (1976). Helv. Chim. Acta59, 1075–1092
Petcher,T.J., Weber,H.P. (1976). Helv. Chim. Acta59, 1480–1488
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Dreyfuss, M., Härri, E., Hofmann, H. et al. Cyclosporin A and C. European J. Appl Microbiol. 3, 125–133 (1976). https://doi.org/10.1007/BF00928431
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DOI: https://doi.org/10.1007/BF00928431