Summary
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1.
Activation of adrenergic receptors in primary cultures of astrocytes and LRM55 glial cells stimulates taurine release.
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2.
Release is inhibited by theβ-adrenergic antagonists alprenolol and propanolol but not by theα-adrenergic antagonist phentolamine.
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3.
Receptor-mediated taurine release occurs via a specific mechanism, since efflux of other amino acids and metabolites is not affected by theβ-adrenergic agonist isoproterenol.
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Shain, W.G., Martin, D.L. Activation ofβ-adrenergic receptors stimulates taurine release from glial cells. Cell Mol Neurobiol 4, 191–196 (1984). https://doi.org/10.1007/BF00711005
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DOI: https://doi.org/10.1007/BF00711005