Summary
The authors report two cases of a rare tumor in adults which were inserted on the fornix and caused a frontal syndrome. By light microscopy, the tumors, highly calcified, were composed of small clear cells forming dense areas in a patchy fibrillary stroma. Electron microscopy revealed a striking neuronal differentiation with numerous synapses. These tumors, for which the term neurocytomas was proposed, were compared with the other CNS neuronal tumors described in the literature.
Article PDF
Avoid common mistakes on your manuscript.
References
Azzarelli B, Richards DE, Anton AH, Roessmann U (1977) Central neuroblastoma. E. M. observations and catecholamine determinations. J Neuropathol Exp Neurol 36:384–397
Boesel CP, Suhan JP, Bradel EJ (1978) Ultrastructure of primitive neurectodermal neoplasms of the central nervous system. Cancer 42:194–201
Gambarelli D, Hassoun J, Choux M, Toga M (1982) Complex cerebral tumor with evidence of neuronal, glial and Schwann cell differentiation. A histological, immunocytochemical and ultrastructural study. Cancer (in press)
Herrick K, Rubinstein LJ (1979) The cytological differentiating potential of pineal parenchymal neoplasms (True pinealomas). Brain 102:289–320
Hirano A, Shin WY (1979) Unatached presynaptic terminals in a cerebellar neuroblastoma in the human. Neuropathol Appl Neurol 5:63–71
Horten BC, Rubinstein LJ (1976) Primary cerebral neuroblastoma: A clinico-pathological study of 35 cases. Brain 99:735–756
Kappers JAV (1976) The mammalian pineal gland, a survey. Acta neurochir 34:109–149
Neuwelt EA, Glasberg M, Frenkel E, Kemp Clark W (1979) Malignant pineal region tumors. A clinico-pathological study. J Neurosurg 51:597–607
Nielsen SL, Wilson CB (1975) Ultrastructure of a “pineocytoma”. J Neuropathol Exp Neurol 34:148–158
Pearl GS, Takei Y (1981) Cerebellar “neuroblastoma”. Nosology as it relates to medulloblastoma. Cancer 47:772–779
Pearl GS, Takei Y, Stefanis GS, Hoffman JC (1981) Intraventricular neuroblastoma in a patient with Von Hippel-Lindau's disease. Light-and electron-microscopic study. Acta Neuropathol (Berl) 53:253–256
Probst A, Ulrich J, Zdrojewski B, Hirt HR (1979) Cerebellar ganglioglioma in a child. J Neuropathol Exp Neurol 38:52–72
Rhodes RH, Davis RL, Kassel SH, Clague BH (1978) Primary cerebral neuroblastoma. A light- and electron-microscopic study. Acta Neuropathol (Berl) 41:119–124
Robertson DM, Hendry WS, Vogel FS (1964) Central ganglioneuroma: A case study using electron microscopy. J Neuropathol Exp Neurol 23:692–705
Rubinstein LJ (1972) Tumors of the central nervous system. Armed Forces Institute of Pathology, Washington, DC
Rubinstein LJ, Herman MM (1972) A light- and electron-microscopic study of a temporal-lobe ganglioglioma. J Neurol Sci 16:27–48
Shin WY, Laufer H, Lee YC, Aftalion B, Hirano A, Zimmerman H (1978) Fine structure of a cerebellar neuroblastoma. Acta Neuropathol (Berl) 42:11–13
Sternberger LA (1979) Immunocytochemistry, 2nd edn. Wiley, New York
Vuia O, Hager H (1975) Central neuroblastic tumour associated with smooth muscle fibers. Eur Neurol 13:258–272
Welsh MG, Reiter RJ (1978) The pineal gland of the gerbil, meriones unguiculatus. I. An ultrastructural study. Cell Tiss Res 193:323–336
Yagishita S, Itoh Y, Chiba Y, Kuda K (1978) Cerebral neuroblastoma. Virchows Arch A [Pathol Anat] 381:1–13
Yagishita S, Itoh Y, Chiba Y, Yamashita T, Nakazima F, Kuwabara T (1980) Cerebellar neuroblastoma. A light and ultrastructural study. Acta Neuropathol (Berl) 50:139–142
Author information
Authors and Affiliations
Additional information
Supported by a grant from the Feglefluc, Marseille, France
Rights and permissions
About this article
Cite this article
Hassoun, J., Gambarelli, D., Grisoli, F. et al. Central neurocytoma. Acta Neuropathol 56, 151–156 (1982). https://doi.org/10.1007/BF00690587
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00690587