Summary
Cold exposed (13°C) mice maintained on a short day photoperiod (9L:15D) became torpid 9 times more frequently than long day photoperiod (16L:8D) animals (Table 1). Mice on a short day photoperiod also exhibited a 26% increase in nesting behavior, a 9% decrease in food consumption and a 49% increase in norepinephrine induced thermogenesis (Table 2). No change in resting metabolism was observed. Similarily, chronic melatonin administration (subcutaneously implanted beeswax pellet containing 3.5 mg melatonin) elicited a 2.5 fold increase in spontaneous daily torpor relative to shamimplanted mice (Table 3). Mice treated with melatonin exhibited a 33% increase in nesting behavior and a slight decrease in food consumption. Although thyroid block (propyl-thiouracil) increased the incidence of daily torpor only slightly, it did effect an 11% decrease in resting metabolism, a 42% decrease in norepinephrine induced thermogenesis and a 5% decrease in food consumption. Thyroid block did not alter nesting behavior.
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Aleksiuk, M., Frohlinger, A.: Seasonal metabolic organization in the muskrat (Ondatra zibethica). I. Changes in growth, thyroid activity, brown adipose tissue, and organ weight in nature. Canad. J. Zool.49, 1143–1155 (1971)
Barry, W.: Environmental effects on food hoarding in deermice (Peromyscus). J. Mammal.57, 731–745 (1976)
Bauman, T.R., Anderson, R.R.: Thyroid activity of the ground squirrel (Citellus tridecemlineatus) using a cannula technique. Gen. Comp. Endocrinol.15, 369–373 (1970)
Brück, K.: Nonshivering thermogenesis and brown adipose tissue in relation to age and their integration in the thermoregulatory system. In: Brown adipose tissue (ed. O. Lindberg), pp. 117–153. New York: Elsevier Press 1970
Chaffee, R., Roberts, J.: Temperature acclimation in birds and mammals. Ann. Rev. Physiol.33, 155–197 (1971)
Eleftheriou, B.E., Zarrow, M.X.: Seasonal variation in thyroid gland activity in deer mice. Proc. Soc. exp. Biol. Med.110, 128–131 (1962)
Ellis, L., Reiter, R.: Endocrine role of the pineal gland. Amer. Zool.16, 1–101 (1976)
Gaertner, R.A., Hart, J.S., Roy, O.Z.: Seasonal spontaneous torpor in the white-footed mouse,Peromyscus leucopus. Comp. Biochem. Physiol.45A, 169–181 (1973)
Hart, J.S.: Rodents. In: Comparative physiology of thermoregulation, Vol. II (ed. G. Causey Whittow), pp. 1–149. New York: Academic Press 1971
Harvey, W.R.: Least squares analysis of data with unequal subclass numbers. Publ. No. ARS-20-8. United States Dept. of Agriculture, Washington, D.C. (1960)
Hayward, J., Lyman, C.P.: Nonshivering heat production during arousal from hibernation and evidence for the contribution of brown fat. In: Proc. III international symposium on natural mammalian hibernation (ed. K.C. Fisher), pp. 346–355. Edinburgh: Oliver and Boyd Press 1967
Heldmaier, G.: Thermogenese der Mausohrfledermaus (Myotis myotis) beim Erwachen aus dem Winterschlaf. Z. vergl. Physiol.63, 59–84 (1969)
Heldmaier, G., Hoffmann, K.: Melatonin stimulates growth of brown adipose tissue. Nature247, 224–225 (1974)
Heroux, O.: Catecholamines, corticosterioids and thyroid hormones in nonshivering thermogenesis under different environmental conditions. In: Physiology and pathology of adaption mechanisms (ed. E. Bajusz), pp. 347–365. New York: Pergamon Press 1969
Hill, R.W.: Daily torpor inPeromyscus leucopus on an adequate diet. Comp. Biochem. Physiol.51A, 413–423 (1975)
Hoffman, R., Reiter, R.: Pineal gland: influence on gonads of male hamsters. Science148, 1609–1611 (1965)
Hoffman, R., Zarrow, M.: Seasonal changes in the basophilic cells of the pituitary gland of the ground squirrel (Citellus tridecemlineatus). Anat. Rec.131, 727–734 (1958)
Hsieh, A., Carlson, L.: Role of the thyroid in metabolic response to low temperature. Amer. J. Physiol.188, 40–44 (1957)
Hudson, J.W.: Torpidity in mammals, In: Comparative physiology of thermoregulation, Vol. II (ed. G. Causey Whittow), pp. 98–158. New York: Academic Press 1973
Hudson, J.W., Deavers, D.: Thyroid function and basal metabolism in the ground squirrelsAmmospermophilus leucurus andSpermophilus spp. Physiol. Zool.49, 425–444 (1976)
Hudson, J.W., Wang, L.: Thyroid function in desert ground squirrels. In: Physiological systems in semiarid environments (ed. C. Hoff, M. Riedesel), pp. 17–35. Univ. New Mexico Press 1969
Janský, L.: Nonshivering thermogenesis and its thermoregulatory significance. Biol. Rev.48, 85–132 (1973)
Janský, L., Hart, J.S.: Participation of skeletal muscle and kidney during nonshivering thermogenesis in cold acclimated rats. Canad. J. Biochem. Physiol.41, 953–964 (1963)
King, J., Maas, D., Weisman, R.: Geographic variation in nest size among species ofPeromyscus. Evolution18, 230–234 (1964)
Lynch, G.R.: Effect of photoperiod and cold acclimation on nonshivering thermogenesis inPeromyscus leucopus. Amer. Zool.10, 308 (1970)
Lynch, G.R., Epstein, A.L.: Melatonin induced changes in gonads, pelage, and thermogenic characters in the white footed mouse.Peromyscus leucopus. Comp. Biochem. Physiol.53C, 67–69 (1976)
Lynch, G.R., Lynch, C.B., Dingle, H.: Photoperiodism and adaptive behavior in mice. Nature244, 46–47 (1973)
Lynch, G.R., Vogt, F.D., Smith, H.R.: Seasonal study of spontaneous daily torpor in the white-footed mouse,Peromyscus leucopus. Physiol. Zool. (in press) (1978)
Mejsmar, J., Janský, L.: Shivering and nonshivering thermogenesis in the bat (Myotis myotis) during arousal from hibernation. Canad. J. Physiol. Pharmacol.48, 102–106 (1970)
Morhardt, J.: Body temperatures of white-footed mice (Peromyscus spp.) during daily torpor. Comp. Biochem. Physiol.33, 423–440 (1970)
Morhardt, J.E., Hudson, J.W.: Daily torpor induced in white-footed mice (Peromyscus sp.) by starvation. Nature212, 1046–1047 (1966)
Morrison, P.: Adaptation of small mammals to the arctic. Fed. Proc.23, 1202–1206 (1964)
Mrovosky, N.: Hibernation and the hypothalamus. New York: Appleton Press 1971
Neumann, R., Cade, T.J.: Photoperiodic influence on the hibernation of jumping mice. Ecology45, 382–384 (1964)
Palmer, D., Riedesel, M.: Responses of whole-animal and isolated hearts of ground squirrels,Citellus lateralis, to melatonin. Comp. Biochem. Physiol.53C, 69–72 (1976)
Pengelley, E., Asmundson, S.: Circannual rhythmicity in hibernating mammals. In: Circannual clocks (ed. E.T. Pengelley), pp. 95–161. New York: Academic Press 1974
Popovic, V.: Endocrines in hibernation. Bull. Museum Comp. Zool.124, 105–129 (1960)
Prosser, C.L.: Comparative animal physiology, p. 966. New York: Saunders 1973
Quay, W.B.: Pireal chemistry in cellular and physiological mechanism, p. 430. Springfield, Illinois: Thomas Press 1974
Rigaudiere, N.: Les variations saisonnières de metabolisme de base et de la thyroide chez les microtines. Arch. Sci. Physiol.23, 215–244 (1969)
Rust, C.C., Meyer, R.K.: Hair color, molt and testes size in male, short-tailed weasels treated with melatonin. Science165, 921–922 (1969)
Salter, W.T.: The control of thyroid activity. In: The Hormones, Vol. II (eds. G. Pincus, K.V. Thimann), pp. 301–349. New York: Academic Press 1950
Sellers, E., You, S.: Role of thyroid in metabolic responses to a cold environment. Amer. J. Physiol.163, 80–91 (1950)
Siegel, S.: Nonparametric statistics for the behavioral sciences. New York: McGraw-Hill 1956
Tashima, L.S.: The effects of cold exposure and hibernation on thyroidal activity ofMesocricetus auratus. Gen. Comp. Endocrinol.5, 267–277 (1965)
Wurtman, R., Axelrod, J., Kelly, D.: The pineal. New York: Academic Press 1968
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Lynch, G.R., White, S.E., Grundel, R. et al. Effects of photoperiod, melatonin administration and thyroid block on spontaneous daily torpor and temperature regulation in the white-footed mouse,Peromyscus leucopus . J Comp Physiol B 125, 157–163 (1978). https://doi.org/10.1007/BF00686752
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DOI: https://doi.org/10.1007/BF00686752