Abstract
Medication of chicks with 125 ppm amprolium or dinitolmide adversely affected oocyst sporulation of Eimeria acervulina (Weybridge strain). Dinitolmide delayed oocyst production and no oocyst wall formation was seen up to 168 h post infection. Both drugs caused large numbers of abnormally small wall-forming bodies to be produced in the macrogametes. In amprolium-fed chicks, abnormal oocyst wall formation was seen. It was concluded that the main drug action was against wall forming bodies of type 2.
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Abbreviations
- C :
-
canaliculi
- CL :
-
cytoplasmic limiting membrane
- L :
-
lipid
- M1, M2, M3 :
-
membranes
- N :
-
nucleus
- NU :
-
nucleolus
- OW :
-
outer oocyst wall
- PG :
-
polysaccharide granule
- PV :
-
parasitophorous vacuole
- WFB1 :
-
wall forming bodies of type 1
- WFB2 :
-
wall forming bodies of type 2
References
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Ball, S.J., Pittilo, R.M., Norton, C.C. et al. Ultrastructural studies of the effects of amprolium and dinitolmide on Eimeria acervulina macrogametes. Parasitol Res 73, 293–297 (1987). https://doi.org/10.1007/BF00531080
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DOI: https://doi.org/10.1007/BF00531080