Zusammenfassung
Einige Polysaccharide, die aus Flechten isoliert wurden, hemmen das Wachstum des Sarkoms-180 in Mäusen und verursachen in vielen Fällen vollständige Regression der Tumoren.
Summary
Some polysaccharides isolated from lichens significantly inhibited the growth of implanted sarcoma-180 in mice and caused complete tumour regression in many cases.
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References
Aspinall, G. O., E. L. Hirst, and M. Warbuster: The alkali-soluble polysaccharide of the lichen, Cladonia alpestris (Reindeer moss). J. chem. Soc. 1955, 651.
Buston, H. W., and V. H. Chambers: Some cell-wall constituents of Cetraria islandica (“Iceland moss”). Biochem. J. 27, 1691 (1933).
Cunningham, W. L., and D. J. Manners: Carbohydrate-metabolizing enzymes. XI. Hydrolysis of lichenin by enzyme preparations from malted barley and Rhizopus arrhizus. Biochem. J. 90, 596 (1964).
Drake, B.: Untersuchungen über einige Polysaccharide der Flechten, vornehmlich das Lichenin und das neuentdeckte Pustulin. Biochem. Z. 313, 388 (1943).
Lindberg, B., and J. McPherson: Studies on the chemistry of lichens. VI. The structure of pustulan. Acta chem. scand. 8, 985 (1954).
Peat, S., W. J. Whelan, J. R. Turvey, and K. Morgan: The structure of isolichenin. J. chem. Soc. 1961, 623.
Perlin, S. A., and S. Suzuki: The structure of lichenin. Selective enzymolysis studies. Canad. J. Chem. 40, 50 (1962).
Shibata, S., Y. Nishikawa, F. M. Cheng, F. Fukuoka, and M. Nakanishi: Antitumour studies on some extracts of Basidiomycetes. Gann (in press) (1968).
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We express our deep thanks to Dr. W. Nakahara, the director of the National Cancer Center Research Institute, for his kind advice, Prof. D. Mizuno for the test against Ehrlich tumour, Prof. B. Lindberg and Prof. S. Peat for the samples of lichen polysaccharides, and to Dr. S. Kurokawa for his kind co-operation in lichenology. We are indebted to Mr. T. Komiya, Mr. L. Xavier Filho and Miss M. Ai for their co-operations in experiments. Thanks are also due to Ministry of Health and Welfare of Japan for grant.
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Shibata, S., Nishikawa, Y., Tanaka, M. et al. Antitumour activities of lichen polysaccharides. Z Krebs-forsch 71, 102–104 (1968). https://doi.org/10.1007/BF00524509
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DOI: https://doi.org/10.1007/BF00524509