Summary
A retrospective technique was used to register all newly diagnosed cases of diabetes mellitus in Norwegian children 0–14 years of age during the ten-year period 1973–1982. A total of 1,914 newly diagnosed cases were detected, from an average population of 932,037 children. The degree of ascertainment was near to 99%. The male incidence exceeded the female incidence by 12% (p<0.02). The mean yearly incidence for the ten-year period was 20.5 per 100,000. Comparing the two five-year periods 1973–1977 and 1978–1982, the mean yearly incidence increased from 18.5 to 22.7 per 100,000 (p<0.0001). There was a marked geographic variation with the highest incidence in the south-east and lower incidence in the northern part of the country. However, in the northern part of the country, there was a remarkable increase of the annual incidence from the first to the second five-year period (12.9 vs 19.3 per 100,000). The highest numbers of new cases were detected in the months of January and October, and the lowest numbers in May and July. The seasonal pattern was significantly different from a uniform distribution of new cases throughout the year (p<0.001). The age-specific incidence increased towards a peak at 12 years for both sexes. In conclusion, Norway has a high and apparently increasing incidence of childhood diabetes. The geographic variation and secular trend present challenging clues for a search of etio-pathogenic factors.
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References
Rewers M (1988) Geographic patterns of childhood insulin dependent diabetes mellitus (IDDM). Diabetes Epidemiology Research International Group. Diabetes 37: 1113–1119
Joner G, Søvik O (1981) Incidence, age at onset and seasonal variation of diabetes mellitus in Norwegian children, 1973–1977. Acta Paediatr Scand 70: 329–335
Reunanen A, Åkerblom HK, Käär ML (1982) Prevalence and ten-year (1970–1979) incidence of insulin-dependent diabetes mellitus in children and adolescents in Finland. Acta Paediatr Scand 71: 893–899
Dahlquist G, Blom L, Holmgren G, Häggöf B, Larsson Y, Sterky G, Wall S (1985) The epidemiology of diabetes in Swedish children 0–14 years — a six-year prospective study. Diabetologia 28: 802–808
Christau B, Kromann H, Ortved Andersen O, Christy M, Buschard K, Arnung K, Højland Kristensen I, Peitersen B, Steinrud J, Nerup J (1977) Incidence, seasonal and geographical patterns of juvenile-onset insulin-dependent diabetes mellitus in Denmark. Diabetologia 13: 281–284
Lestradet H, Besse J (1977) Prévalence et incidence du diabète juvénile insulino-dépendent en France. Diabète Métab 3: 229–234
Matsuura N, Fukushima N, Fukita H, Abe K, Yamada Y, Kashiwao N, Fujieda K, Kata T, Mikami Y, Nohara Y, Fukuda K, Okunu A, Taguchi T, Oyanagi K (1983) Epidemiologic survey of juvenile-onset insulin dependent diabetes mellitus (IDDM) in Hokkaido, Japan, 1973–1981. Tohoku J Exp Med 141 [Suppl]: 181–189
Westlund K (1966) Incidence of diabetes mellitus in Oslo, Norway 1925 to 1954. Br J Prev Soc Med 20: 105–116
Bratlid D (1976) A preliminary study on the incidence of juvenile diabetes mellitus in Northern Norway. Nordic Council Arct Med Res Rep 15: 54–57
Ustvedt HJ, Olsen E (1977) Incidence of diabetes mellitus in Oslo, Norway 1956–1965. Br J Prev Soc Med 31: 251–257
Sterky G, Holmgren G, Gustavson KH, Larsson Y, Lundmark KM, Nilsson KO, Samuelson G, Thalme B, Wall S (1978) The incidence of diabetes mellitus in Swedish children 1970–1975. Acta Paediatr Scand 67: 139–143
Åkerblom HK, Reunanen A, Käär ML (1980) The incidence of insulin-dependent diabetes mellitus in 0–14 year old children in Finland in 1970–1978. Nordic Council Arct Med Res Rep 26: 60–66
Bishop YMM, Fienberg SE, Holland PW (1974) Discrete multivariate analysis: theory and practice. MIT Press, Massachusetts, pp 231–233
Rosner B (1986) Fundamentals of Biostatistics. 2nd edn. Duxburry Press, Boston
North AF, Gorwitz K, Sultz HA (1977) A secular increase in the incidence of juvenile diabetes mellitus. J Paediatr 91: 706–710
Lorenzi M, Cagliero E, Schmidt NJ (1985) Racial differences in the incidence of juvenile-onset Type 1 diabetes: epidemiologic studies in southern California. Diabetologia 28: 734–738
Stewart-Brown S, Haslum M, Butler N (1983) Evidence for increasing prevalence of diabetes mellitus in childhood. Br Med J 286: 1855–1857
Patterson CC, Thorogood M, Smith PG, Heasman MA, Clarke JA, Mann JI (1983) Epidemiology of Type 1 (insulin-dependent) diabetes in Scotland 1968–1976: evidence of an increasing incidence. Diaibetologia 24: 238–243
Green A, Andersen PK (1983) Epidemiological studies of diabetes mellitus in Denmark, 3. Clinical characteristics and incidence of diabetes among males aged 0 to 19 years. Diabetologia 25: 226–230
LaPorte RE, Fishbein HA, Drash AL, Kuller LH, Schneider BB, Orchard T, Wagener DK (1981) The incidence of insulin-dependent diabetes mellitus in Allegheny County, Pennsylvania (1965–1976). Diabetes 30: 279–284
Siemiatycki J, Colle E, Aubert D, Campbell S, Belmonte MM (1986) The distribution of Type I (insulin-dependent) diabets mellitus by age, sex, secular trend, seasonality, time clusters and space-time clusters: evidence from Montreal, 1971–1983. Am J Epidemiol 124: 545–560
Vaandrager GJ, Braining GJ, Veenhof FJ, Drayer NM (1984) Incidence of childhood diabetes in The Netherlands: a decrease from north to south over North-Western Europe? Diabetologia 27: 203–206
Dahlquist G, Gustavson KH, Holmgren G, Hagglöf B, Larsson Y, Nilsson KO, Samuelson G, Sterky G, Thalme B, Wall S (1982) The incidence of diabetes mellitus in Swedish children 0–14 years of age. A prospective study 1977–1980. Acta Paediatr Scand 71: 7–14
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Joner, G., Søvik, O. Increasing incidence of diabetes mellitus in Norwegian children 0–14 years of age 1973–1982. Diabetologia 32, 79–83 (1989). https://doi.org/10.1007/BF00505178
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DOI: https://doi.org/10.1007/BF00505178