Summary
Reference materials to meet multipurpose needs for analysis of both inorganic and organic constituents in biological investigations are not readily available. A human total diet material is being investigated as a reference material for a wide variety of constituents of interest to human nutrition and health. This material shows a stable assay value for the natural levels of a number of vitamins following freeze-drying or radiation sterilization. This is an important feature in producing materials for long term stability as a Reference Material for natural levels of these constituents. An exception is an increase of 34% in assay value of folic acid upon freeze-drying and an 85% increase upon freezedrying followed by radiation sterilization.
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Iyengar, V., Wolf, W.R. & Tanner, J. Multipurpose biological reference materials. Z. Anal. Chem. 332, 549–551 (1988). https://doi.org/10.1007/BF00472640
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DOI: https://doi.org/10.1007/BF00472640