Abstract
Whereas late manifestations of Lyme borreliosis were described in Russia more than 100 years ago, early manifestations were described as different disease entities such as tick-borne erythema, etc. In 1985 Lyme borreliosis was first verified serologically and the agent was first identified in 1986. By the beginning of 1992 Lyme borreliosis was serologically confirmed in patients from the Baltics to the Far East.
Their geographical patterns in Russia are closely related to areas of the hard ticks Ixodes persulcatus and Ixodes ricinus which are also the main vectors of tick-borne encephalitis virus. As in the case of this infection, in the west of Russia there are “ricinus” natural foci of Lyme borreliosis, and to the east there are similar “persulcatus” foci; through large territories in the East Europe there are common foci for both species. Many Borrelia burgdorferi strains of tick origin have been isolated from various regions of Russia and neighbouring republics. Adult tick infection rates vary from several per cent to 30% in I. ricinus and up to 50–60% in I. persulcatus. Double infections of Lyme borreliosis spirochetes and tick-borne encephalitis virus have been recorded for ticks as well as for humans. Lyme borreliosis morbidity and its importance for the Russia territory are discussed.
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References
Afzelius A. (1910): Verhandlungen der dermatologischen Gesellschaft in Stockholm -Arch. Dermatol. Syph., 101: 405–406.
Ananyeva L.P., Korenberg E.I., Skripnikova I.A., Soldatkina L.M. and Nasonova V.A. (1990): Clinical and serological study of Lyme disease in the northwestern parts of the USSR -Med. Parasitol. and Parasitic Diseases, 6: 28–31 (In Russian).
Åsbrink E. (1985): Erythema chronicum migrans Afzelius and Acrodermatitis chronica atrophicans. Early and late manifestations of Ixodes ricinus-borne Borrelia spirochetes -Acta Derm. Venereol. (Stockh.), suppl. 118: 1–63.
Barbour A.G. (1984): Isolation and cultivation of Lyme disease spirochetes -The Yale Journal of Biology and Medicine, 57: 71–76.
Barbour A.G. and Korenberg E.I. (1991): The agent of Lyme disease. In: “Problems of Infectology”, Moscow, “Medicina”, 181–187 (In Russian).
Burgdorfer W. (1986): Discovery of the Lyme disease spirochete -Zbl. Bact. Hyg., 263: 7–10.
Chengxu Ai, Yuxin W. and Yongguo Z. (1988): Clinical manifestations and epidemiological characteristics of Lyme disease in Hailin County, Heilongjiang Province, China -Annals of the New York Acad. Sci., 539: 302–313.
Dekonenko E.P. (1985): About an etiology of Erythema migrans in the USSR. In: “Second International Symposium on Lyme disease and related disorders. Vienna, Austria, Sept. 17–19,. Compendium of Abstracts”, 68.
Dekonenko E.P. (1988): Clinical manifestations of tick-borne erythema in the USSR -Annals of New York Acad. Sci., 539: 452–453.
Dekonenko E.P., Smirnov Yu.K. and Umansky K.G. (1985): Disturbances of the nervous system during tick-borne annular erythema -J. Neuropathol. and Psychiatrics, 85: 539–545 (In Russian).
Dekonenko E.P., Smirnov Yu.K. and Umansky K.G. (1986): Clinical and epidemiological character of annular tick-borne erythema -Med. Parasitol. and Parasitic Diseases, 3: 75–79 (In Russian).
Dekonenko E.P., Steere A., Berardi V. and Kravchuk L.N. (1988): Lyme borreliosis in the Soviet Union: a cooperative US-USSR report -J. Infect. Diseases, 158: 748–753.
Dekonenko E.P., Steere A.C. and Kravchuk L.N. (1988): Results of the clinical and immunological studies of patients with Lyme tick-borne borreliosis -Med. Parasitol. and Parasitic Diseases, 4: 55–58 (In Russian).
Dekonenko E.P., Steere A.C. and Umansky K.G. (1989): Clinical signs and diagnostics of Lyme borreliosis -Therapeutic Archives, 4: 116–120 (In Russian).
Dekonenko E.P. and Umansky K.G. (1987): Tick-borne erythema (a review) -J. Neuropathol. and Psychiatrics, 87: 283–289 (In Russian).
Hanson H.S., von Stedingk L.-V., HovmarkA., Åsbrink E., Korenberg E. and Kryuchechnikov V.N. (1989): Electrophoretic analysis of the protein pattern in different isolates of Borrelia burgdorferi. In: Scandinavian Electrophoresis Society Second Congress. Sandefjord, Norway, June 4–7, 87.
Kawabata M., Baba S. and Iguchi K. (1987): Lyme disease in Japan and its possible incriminated tick vector, Ixodes persulcatus -J. Infect. Diseases, 156: 854.
Kovalevsky Yu.V., Korenberg E.L. and Nikitochkin I.G. (1991): Optimization of the technique assessing contamination and degree of individual tick infestation with borrelia -Med. Parasitol. and Parasitic Diseases, 3: 18–21 (In Russian).
Korenberg E.I., Kalinin M.I., Skripnikova I.A. and Soldatkina L.M. (1990): Experience of serological screening of the rural population within Lyme borreliosis endemic territory -Med. Parasitol. and Parasitic Diseases, 3: 15–16 (In Russian).
Korenberg E.I. and Kovalevsky Yu.V. (1981): Regionalization of the tick-borne encephalitis area. In: “Advances in science and technology. Medical geography” — Moscow, “VINITI” 11: 148 (In Russian).
Korenberg E.I., Kovalevsky Yu.V., Kryuchechnikov V.N. and Gorelova N.B. (1991): Tick Ixodes persulcatus Schulze, 1930 as a vector of Borrelia burgdorferi. In: “Modern Acarology”, Academia, Prague 1: 119–123.
Korenberg E.I., Kovalevsky Yu.V., Kuznetsova R.L., Fonarev L.S., Churilova A.A., Antykova L.P., Kalinin M.I., Kryuchechnikov V.N., Mebel B.D., Scherbakov S.V. and Kovtunenko S.S. (1988): Detection and primary results of Lyme disease investigation in the North-West of the USSR -Med. Parasitol. and Parasitic Diseases, 1: 45–48 (In Russian).
Korenberg E.I., Kryuchechnikov V.N., Ananyina Yu.V. and Chernukha Yu.G. (1986): Prerequisites of the existence of Lyme disease in the USSR -Zbl. Bact. Hyg., 263: 471–472.
Korenberg E.I., Kryuchechnikov V.N., Dekonenko E.P., Scherbakov S.V. and Ananyina Yu.V. (1985): Serological detection of Lyme disease in the USSR -J. Microbiol., Epidemiol. and Immunobiol., 6: 111–113 (In Russian).
Korenberg E.I., Kryuchechnikov V.N., Kovalevsky Yu.V., Scherbakov S. V., Kuznetsova R.I. and Levin M.L. (1987): Ixodes persulcatus Schulze — a new vector of Borrelia burgdorferi. Reports of the USSR Academy of Sciences, 297: 1268–1270 (In Russian).
Korenberg E.I., Kuznetsova R.I., Kovalevsky Yu.V., Vasilenko Z.E and Mebel B.D. (1991): Basic epidemiological properties of Lyme disease in the North-West of the USSR -Med. Parasitol. and Parasitic Diseases, 3: 14–17 (In Russian).
Korenberg E.I., Scherbakov S. V., Bannova G. G., Levin M.L. and Karavanov A.S. (1990): Infection of Ixodes persulcatus ticks by both Lyme borreliosis and tick-borne encephalitis agents simultaneously -Parasitology (Leningrad), 24: 102–105 (In Russian).
Korenberg E.I., Scherbakov S.V., Kovalevsky Yu.V., KryuchechnikovV.N. and Nikitina O.V. (1988): Borrelia burgdorferi transmission from nymphs to adults of Ixodes persulcatus Schulze ticks -Reports of the USSR Academy of Sciences, 302: 759–760 (In Russian).
Korenberg E.I., Scherbakov S.V. and Kryuchechnikov V.N. (1987): Lyme disease prevalence in the USSR -Med. Parasitol. and Parasitic Diseases, 2: 71–73 (In Russian).
Korenberg E.I., Scherbakov S.V., Zakharycheva T.A., Levin M.L., Kalinin M.I. and Kryuchechnikov V.N. (1989): Lyme disease in the Khabarovsk Territory -Med. Parasitol. and Parasitic Diseases, 5: 74–78 (In Russian).
Kryuchechnikov V.N. (1985): Erythema chronicum migrans or Lyme disease — a new tick-borne spirochetosis -J. Microbiol., Epidemiol. and Immunobiol., 9: 101–109 (In Russian).
Kryuchechnikov V.N., Korenberg E.I. and Scherbakov S.V. (1988): Identification of borrelia isolated in the USSR from Ixodes persulcatus ticks -J. Microbiol., Epidemiol. and Immunobiol., 12: 41–44 (In Russian).
Kryuchechnikov V.N., Korenberg E.I., Scherbakov S.V., Gorelova N.B., Jurzitsova Z., Galouzka Z., Kovalevsky Yu.V., Levin M.L.and Bunikis I.A. (1990): Identification of borrelia isolated in the Soviet Union and Czechoslovakia from Ixodes ricinus (L.) ticks -J. Microbiol., Epidemiol. and Immunobiol., 6: 10–13 (In Russian).
Kuznetsova R.I, Shapoval A.N. and Churilova A.A. (1967): About tick-borne erythema. In: “The Pasteur Institute with the participation of representatives of Sanitary-Epidemiological Stations from North-Western regions: Resulting Conference. Summaries and short communications”, Leningrad, 177–178 (In Russian).
Lane R., Piesman J. and Burgdorfer W. (1991): Lyme borreliosis: Relation of its causative agent to its vectors and hosts in North America and Europe -Annu. Rev. Entomol. - Palo Alto (Calif.), 36: 587–609.
Lyme borreliosis — Report on a WHO Workshop (1991): EUR/HFA target 4.
Lysovskaya N.D. (1958): Materials for the study of Acrodermatitis chronica atrophicans. Thesis for the Candidate of Medical Sciences Degree, Leningrad pp. 263 (In Russian).
Magazanik S.S. and Pogodina V.V. (1960): About dermal-erythematous reactions during tick-borne encephalitis -Clinical Medicine, 9: 59–64 (In Russian).
Mebel B.D., Beitrishvili G.A., Zhivich M.B., Osetrov B.A., Kuznetsov R.I., Korenberg E.I. and Kalinin M.I. (1988): Clinical picture of acute period in Lyme tick borne borreliosis -Med. Parasitol. and Parasitic Diseases, 3: 30–33 (In Russian).
Meshchersky G.I. (1898–1899): To the question on Atrophia cutis idiopathica progressiva -Protocols of Moscow Venerological and Dermatological Society, 8: 135–160 (In Russian).
Motejunas L.L, Korenberg E.I., Daujotas S. V, Kalinin M.I., Shadjenje A.R., Regalenje G.K. and Scherbakov S.V. (1989): Primary results of the studies on natural focality of Lyme disease in Lithuania. In: “XII All-Union Conference on Natural Focality of Diseases”, Moscow, 108–109 (In Russian).
Nickolsky P.V. (1896): Demonstration of the case of Atrophia cutis maculata. Diary of VI Congress of the Society of Russian Physicians devoted to the memory of N.I. Pirogov. Kiev, 12: 89 (In Russian).
Panov A.G. (1956): Tick-borne encephalitis “Medgiz”, Moscow, pp. 283 (In Russian).
Pismenny N.N. (1902): A case of idiopathic acquired atrophia of derma -Medical Review, 37: 710–713 (In Russian).
Pospelov A.I. (1886): Two cases of independent dermal atrophia of adults -Medical Review, 26: 565–574.
Pospelov A.I. (1905): Guide-book for investigations of dermatological diseases — Moscow, pp. 650 (In Russian).
Reichuk E.A., Chernukha Yu.G. and Petrov E.M. (1989): Lyme disease in the Kaliningrad region. In: “XII All-Union Conference on Natural Focality of Diseases”, Moscow, 135–136 (In Russian).
Smirnov Yu.K., Vladimirova V.V. and Umansky K.G. (1977): About treatment of patients with annular erythema after tick bite -J. Neuropathol. and Psychiatrics, 77: 182–185 (In Russian).
Steere A.C., Snydman D., Murray P., Mensch J., Main A., Walls R., Shope R. and Malavista S. (1986): Historical perspective of Lyme disease -Zbl. Bact. Hyg., 263: 3–6.
Umansky K.G., Sarmanova E.S. and Pivanova G.P. (1962): Does the erythematous form of tick-borne encephalitis exist? In: “Tick-borne encephalitis and other arboviral infections”, Moscow Minsk, 182–183 (In Russian).
Wilske B., Preac-Mursic V., Schierz G., Kuhbeck R., Barbour A. and Kramer M. (1988): Antigenic variability of Borrelia burgdorferi -Annals of the New York Academy of Sciences, 539: 126–143.
Yuxin W., Chenghu Ai and Yougguo Z. (1988): Spirochetes isolated from the blood of three cases of Lyme disease with neurologic abnormalities -Acta Microbiologica Clinica, 28: 275–278.
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Korenberg, E.I., Kryuchechnikov, V.N. & Kovalevsky, Y.V. Advances in investigations of lyme borreliosis in the territory of the former USSR. Eur J Epidemiol 9, 86–91 (1993). https://doi.org/10.1007/BF00463095
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DOI: https://doi.org/10.1007/BF00463095