Abstract
The occurrence of mycotoxins, in agricultural commodities is a worldwide problem with almost all commodities being potentially susceptible to contamination under the proper conditions. The genera of fungi most implicated are Aspergillus, Penicillium and Fusarium, although the potential for toxin production varies considerably within any given species.
Conditions that affect toxin production include fungal strain variation, genetic susceptibility of the host plant or commodity, moisture content, commodity composition, temperature, aeration, microbial population and stress factors. There is undoubtedly interaction between these factors so that laboratory studies involving limited variables can only, at best, approximate field conditions.
Natural contamination with mycotoxins has been reported for most of the major agricultural commodities in the world including corn, wheat, rice, millet, barley, oats, sorghum, peanuts, beans, copra, some fruits and nuts and various forages; strangely, soybeans do not appear to be involved to any major extent. The major mycotoxins on commodities reported to date include aflatoxin, the trichothecenes, ochratoxin, citrinin, zearalenone, sporidesmins and some tremorgens. However, laboratory studies have shown that the fungi are capable of producing hundreds of toxic chemicals, most of which are not included in routine analyses. In addition, since toxin effects are often insidious and may go undetected, the true dimensions of the mycotoxin problem are unknown.
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Aust, S. D., H. P. Broquist & K. L. Rinehart, Jr. 1968. Slaframine: A parasympathomimetric from Rhizoctonia leguminicola. Biotechnol. Bioeng. 10: 403–412.
Ciegler, A. J. L. Richard, J. J. Ellis & S. J. Cysewski. 1972. Studies of the toxicity of Helminthosporium maydis. Appl. Microbiol. 23: 586–591.
Ciegler, A., R. F. Vesonder & R. J. Cole. 1976. Tremorgenic mycoloxins. In: Mycotoxins and Other Fungal-Related Food Problems. J. V. Rodnicks (ed.). Advances in Chemistry Series 149, Am. Chem. Soc., Washington, D. C., pp. 163–177.
Ellis, J. J. & S. G. Yates. 1971. Mycotoxins of fungi from fescue. Econ. Bot. 25: 1–5.
Eppley, R. M. & W. J. Bailey. 1973. 12, 13-Epoxy- 9- trichothecenes as the probable mycotoxins responsible for stachybotryotoxicosis. Science 181: 758–760.
Gupta, S. K. & T. A. Venkitasubramanian. 1975. Production of aflatoxin on soybeans. Appl. Microbiol. 29: 834–836.
Hesseltine, C. W. 1974. Natural occurrence of mycotoxins in cereals. Mycopathol. Mycol. Appl. 53: 141–153.
Krogh, P., B. Hald & E. J. Pedersen. 1973. Occurrence of ochratoxin A and citrinin in cereals associated with mycotoxic porcine nephropathy. Acta Pathol. Microbiol. Scand. (B) 81: 689–695.
Krogh, P., Hald, P. Englund, L. Rutqvist & O. Swahn. 1974. Contamination of Swedish cereals with ochratoxin A. Acta Pathol. Microbiol. Scand. (B) 82: 301–302.
Leigh, C. & A. Taylor. 1976. The chemistry of epipolythiopiperazine-3,6-diones. In: Mycotoxins and Other Fungal-Related Food Problems. J. V. Rodnicks (ed.). Advances in Chemistry Series 149, Am. Chem. Soc., Washington, D.C., pp. 228–275.
Lillehoj, E. B. & A. Ciegler. 1975. Mycotoxin synergism. In: Microbiology-1975. Am. Soc. Microbiol., Washington, D. C., pp. 344–358.
Lillehoj, E. B., D. I. Fennell & W. F. Kwolek. 1976. Aspergillus flavus and aflatoxin in Iowa corn before harvest. Science 193: 495–496.
Marsh, P. B., M. E. Simpson, G. O. Craig, J. Denoso & H. H. Ramey, Jr. 1973. Ocurrence of aflatoxins in cottonseeds at harvest in relation to location of growth and field temperatures. J. Environ. Qual. 2: 276–281.
Pathre, S. V. & C. J. Mirocha. 1976. Zearalenone and related compounds. In: Mycotoxins and Other Fungalrelated Food Problems. J. V. Rodnicks (ed.). Advances in Chemistry Series 149, Am. Chem. Soc., Washington, D. C., pp. 178–227.
Russell, T. E., T. F. Watson & G. F. Ryan. 1976. Field Field accumulation of aflatoxin in cottonseed as influenced by irrigation termination dates and pink bollworm infestation. Appl. Microbiol. 31: 711–713.
Scott, P. M., W. F. Miles, P. Toft & J. G. Dube. 1972. Occurrence of patulin in apple juice. J. Agric. Food Chem. 20: 450–451.
Scott, P. M., W. van Walbeek, B. Kennedy & D. Anyeti. 1972. Mycotoxins(ochratoxin A, citrinin and sterigmatocystin) and toxigenic fungi in grains and other agricultural products. J. Agric. Food Chem. 20: 1103–1109.
Shotwell, O. L., C. W. Hesseltine, E. E. Vandegraft & M. L. Goulden. 1971. Survey of corn from different regions for aflatoxins, ochratoxin and zearalenone. Cereal Sci. Today 16: 266–273.
Stoloff, L. 1976. Occurrence of mycotoxins in foods and feeds. In: Mycotoxins and Other Fungal-Related Food Problems. J. V. Rodricks (ed.). Advances in Chemistry Series 149, Am. Chem. Soc., Washington, D. C., pp. 23–50.
Uchiyama, M., E. Isohata & Y. Takeda. 1976. A case report on the detection of ochratoxin A from rice. J. Food Hyg. Soc. 17: 103–104.
Ukai, T., Y. Yamamoto & T. Yamamoto. 1954. Substance from a strain of Penicillium. II. Culture method of Hori-Yamamoto strain and chemical structure of its poisonous substance. J. Pharm. Soc. Jpn. 74: 450–461.
Vesonder, R. F., A. Ciegler, A. H. Jensen, W. K. Rohwedder & D. Weisleder. 1976. Co-identity of the refusal and emetic principle from Fusarioum-infected corn. Appl. Environ. Microbiol. 31: 280–285.
Wilson, D. M. & G. J. Nuovo. 1973. Patulin production in apples decayed by Penicillium expansum. Appl. Microbiol. 26: 124–125.
Wilson, B. J., C. H. Wilson & A. W. Hayes. 1068. Tremorgenic toxin from Penicillium cyclopium grown on food materials. Nature (London) 220: 77–78.
Zuber, M. S., O. H. Calvert, E. B. Lillehoj & W. F. Kwolek. 1976. Preharvest-development of aflatoxin B1 in corn in the United States. Phytopathology 66: 1120–1121.
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Ciegler, A. Fungi that produce mycotoxins: Conditions and occurrence. Mycopathologia 65, 5–11 (1978). https://doi.org/10.1007/BF00447169
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DOI: https://doi.org/10.1007/BF00447169