Summary
In 6 patients undergoing cardiac catheterization (in whom shunts were excluded) simultaneously sampled central venous and arterial blood specimens were analyzed for insulin, free fatty acids and glucose. Insulin levels were usually (4/6) 15–19% lower in arterial than central venous blood, but once was only 10% lower and once 8% higher. No consistent differences in central venous and arterial blood were noted for either free fatty acids or glucose.
Résumé
On a analysé l'insuline, les acides gras libres et le glucose du sang artériel et veineux central sur 6 patients soumis à un cathétérisme cardiaque (les communications anormales entre la circulation pulmonaire et systémique ont été exclues). Chez 4 des 6 patients les taux d'insuline du sang artériel étaient inférieurs de 15–19% à ceux du sang veineux central; mais chez un des 6 patients il n'était inférieur que de 10% et chez un autre il était supérieur de 8%. On n'a pas observé de différences importantes dans le sang veineux et artériel central pour les acides gras libres ou pour le glucose.
Zusammenfassung
Bei 6 Patienten, bei denen eine Katheterisierung des Herzens vorgenommen wurde (wobei sich das Vorliegen eines Shunt ausschließen ließ), wurden gleichzeitig zentral-venöse und arterielle Blutproben entnommen. In diesen wurden Insulin, freie Fettsäuren und Glucose bestimmt. Bei 5 Patienten lag der Insulinspiegel im arteriellen Blut um 13% tiefer als im venösen Blut. Dieser Befund läßt einen Insulinverbrauch oder eine Insulinaktivierung in der Lunge vermuten. Im Hinblick auf freie Fettsäuren und Glucose ließen sich im zentralvenösen und im arteriellen Blut keine wesentlichen Differenzen feststellen.
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Rubenstein, A.H., Zwi, S. & Miller, K. Insulin and the lung. Diabetologia 4, 236–238 (1968). https://doi.org/10.1007/BF00430101
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DOI: https://doi.org/10.1007/BF00430101