Summary
This study examined the rates of gastric emptying for water and 13 different carbohydrate-containing solutions in seven subjects, using conventional gastric intubation techniques. The rates of gastric emptying for water and a 10% glucose-polymer solution were also measured during 90 min of treadmill running at 75% of each subject's maximum oxygen consumption \((\dot V_{O_{2 max} } )\). At rest, 15% glucose-polymer (P) and fructose (F) solutions emptied more rapidly from the stomach and provided a faster rate of carbohydrate delivery than did a 15% glucose (G) solution (p<0.05). The G solutions showed a constant energy delivery rate of 3.3 kcal · min−1; energy delivery from P and F solutions rose with increasing solution concentrations. The osmolality of the gastric aspirate predicted the rate of gastric emptying for all solutions (p<0.05) but overestimated rates of emptying for 10% and 15% P solutions and underestimated emptying rates for 10% and 15% F solutions. Exercise at 75% \(\dot V_{O_{2 max} }\) decreased the rate of gastric emptying of water but not of 10% P solutions. Thus the different rates of gastric emptying for different carbohydrate-containing solutions were not entirely explained by differences in osmolality. Furthermore, exercise may have different effects on the gastric emptying rates of water and carbohydrate solutions.
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References
Barker GR, Cochrane GMcl, Corbett GA, Hunt JN, Roberts SK (1974) Actions of glucose and potassium chloride on osmoreceptors slowing gastric emptying. J Physiol 237:183–186
Barker GR, Cochrane GMcl, Corbett GA, Dufton JF, Hunt JN, Roberts SK (1978) Glucose, glycine and diglycine in test meals as stimuli to a duodenal osmoreceptor slowing gastric emptying. J Physiol 283:341–346
Brener W, Hendrix TR, McHugh PR (1983) Regulation of gastric emptying of glucose. Gastroenterology 85:76–82
Cammack J, Read NW, Cann PA, Greenwood B, Holgate AM (1982) Effect of prolonged exercise on the passage of a solid meal through the stomach and small intestine. Gut 23:957–961
Campbell JMH, Mitchell GO, Powell ATW (1928) The influence of exercise on digestion. Guy's Hosp Rep 78:279–293
Churms SC, Stephen AM (1971) The determination of molecular-weight distributions of maize starch dextrins by gel chromatography. J S Afr Chem Inst 24:177–185
Costill DL, Saltin B (1974) Factors limiting gastric emptying during rest and exercise. J Appl Physiol 37:679–683
Coyle EF, Costill DL, Fink WJ, Hoopes DG (1978) Gastric emptying rates for selected athletic drinks. Res Q 49:119–124
Crandall LA (1928) The effect of physical exercise on the gastric secretion. Am J Physiol 84:48–55
Crane R (1968) Absorption of sugars. In: Handbook of physiology — alimentary canal IV. American Physiological Society, Washington, DC, pp 1323–1351
Elias E, Gibson GJ, Greenwood LF, Hunt JN, Tripp JH (1968) The slowing of gastric emptying by monosaccharides and disaccharides in test meals. J Physiol 194:317–326
Fordtran JS, Ingelfinger FJ (1968) Absorption of water, electrolytes and sugars from the human gut. In: Handbook of physiology — alimentary canal IV. American Physiological Society, Washington, DC, pp 1457–1489
Fordtran JS, Saltin B (1967) Gastric emptying and intestinal absorption during prolonged severe exercise. J Appl Physiol 12:331–335
Foster C, Costill DL, Fink WJ (1980) Gastric emptying characteristics of glucose and glucose-polymer solutions. Res Q 51:299–305
Hellenbrandt FA, Hoopes SL (1934) Studies in the influence of exercise on the digestive work of the stomach. I. Its effect on the secretory cycle. Am J Physiol 107:348–354
Hunt JN (1960) The site of receptors slowing gastric emptying in response to starch in test meals. J Physiol 154:270–276
Hunt JN (1961) The osmotic control of gastric emptying. Gastroenterology 41:49–51
Hunt JN (1963) The duodenal regulation of gastric emptying. Gastroenterology 45:149–156
Hunt JN (1983) Does calcium mediate slowing of gastric emptying by fat in humans; Am J Physiol 24:G89-G94
Hunt JN, Knox MT (1968) Regulation of gastric emptying. In: Handbook of physiology — alimentary canal IV. American Physiological Society, Washington, DC, pp 1917–1935
Hunt JN, McHugh PR (1982) Does calcium mediate the slowing of gastric emptying in primates? Am J Physiol 243:G200-G203
Hunt JN, Pathak JD (1960) The osmotic effects of some simple molecules and ions on gastric emptying. J Physiol 143:254–269
Hunt JN, Stubbs DF (1975) The volume and energy content of meals as determinants of gastric emptying. J Physiol 245:209–225
Ivey KJ, Schedl HP (1970) Gastric nonabsorbable indicators for studies in man. Gastroenterology 59:234–239
Konturek S, Tasler J, Obtulowicz W (1973) Effect of exercise on gastrointestinal secretions. J Appl Physiol 34:324–328
Mallinson CN (1968) Effect of pancreatic insufficiency and intestinal lactase deficiency on the gastric emptying of starch and lactose. Gut 9:737–741
McHugh PR, Moran TH (1979) Calories and gastric emptying: a regulatory capacity with implications for feeding. Am J Physiol 236:R254-R260
Moran TH, McHugh PR (1981) Distinctions among three sugars in their effects on gastric emptying and satiety. Am J Physiol 241:R25-R30
Neufer PD, Costill DL, Fink WJ, Kirwan JP, Fielding RA, Flynn MG (1986) Effects of exercise and carbohydrate composition on gastric emptying. Med Sci Sports Exerc 18:658–662
Owen MD, Kregel KC, Wall PT, Gisolfi CV (1986) Effects of ingesting carbohydrate beverages during exercise in the heat. Med Sci Sports Exerc 18:568–575
Ramsbottom N, Hunt JN (1974) Effects of exercise on gastric emptying and gastric secretion. Digestion 10:1–8
Schedl HP, Miller D, White D (1966) Use of polyethylene glycol and phenol red as unabsorbed indicators for intestinal absorption studies in man. Gut 7:159–163
Scrimgeour AG, Noakes TD, Adams B, Myburgh K (1986) The influence of weekly training distance on fractional utilization of maximum aerobic capacity in marathon and ultramarathon runners. Eur J Appl Physiol 55:202–209
Seiple RS, Vivian VM, Fox EL, Bartels RL (1983) Gastric-emptying characteristics of two glucose polymer-electrolyte solutions. Med Sci Sports Exerc 15:366–369
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Sole, C.C., Noakes, T.D. Faster gastric emptying for glucose-polymer and fructose solutions than for glucose in humans. Europ. J. Appl. Physiol. 58, 605–612 (1989). https://doi.org/10.1007/BF00418506
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DOI: https://doi.org/10.1007/BF00418506