Summary
Scalp penetration of 7 hair dyes (oxidative and direct) that occurs under conditions of hair dye usage was evaluated for both rhesus monkey and man using 14C labeled materials by quantifying their absorbtion via urine assays. Both species showed a remarkably similar pattern of dye penetration. The extent of scalp penetratoon is slightly higher for direct dyes but in neither case does it exceed 1% of the applied dose.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Feldmann RJ, Maibach HI (1970) Absorption of some organic compounds through the skin of man. J Invest Dermatol 54:399–404
Maibach HI, Wolfram LJ (1981) Percutaneous penetration of hair dyes. J Soc Cosmet Chem 32:223–229
Tsomi V, Kalopissis G (1982) Cutaneous penetration of some hair dyes in the hairless rat. Toxicol Eur Res 4:119–127
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Wolfram, L.J., Maibach, H.I. Percutaneous penetration of hair dyes. Arch Dermatol Res 277, 235–241 (1985). https://doi.org/10.1007/BF00404323
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00404323