Abstract
An oscillatory intersegmental neuronal network drives the swimming rhythm of the leech. This network consists of interneurons joined via inhibitory connections to form a series of segmentally iterated, concatenated rings. Recurrent cyclic inhibition in these rings produces a multiphasic activity rhythm. By theoretical analysis of such concatenated interneuronal rings and construction of their electronic analogs it is shown that the interneural network identified in the central nervous system of the leech has properties appropriate for generating the observed motor output.
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Ádám,A.: Simulation of rhythmic nervous activities. II. Mathematical models for the function of networks with cyclic inhibition. Kybernetik 5, 103–109 (1968)
Alving,B.O.: Spontaneous activity in isolated somata of Aplysia pacemaker neurons. J. gen. Physiol. 45, 29–45 (1968)
Bullock,T.H.: The origins of patterned nervous discharge. Behavior 17, 48–59 (1961)
Dunin-Barkovskii,V.L.: Fluctuations in the level of activity in simple closed neurone chains. Biofizika 15, 374–378 (1970)
Friesen,W.O., Poon,M., Stent,G.S.: An oscillatory neuronal circuit generating a locomotory rhythm. Proc. Nat. Acad. Sci. USA 73, 3734–3738 (1976)
Friesen,W.O., Poon,M., Stent,G.S.: Neuronal control of swimming in the medicinal leech. IV. Identification of a network of oscillatory interneurons. Submitted for publication (1977)
Kling,V., Székely,G.: Simulation of rhythmic nervous activities. I. Function of networks with cyclic inhibitions. Kybernetik 5, 89–103 (1968)
Kristan,W.B.,Jr., Calabrese,R.L.: Rhythmic swimming activity in neurons of the isolated nerve cord of the leech. J. exp. Biol. 63, 643–666 (1976)
Kristan,W.B.,Jr., Stent,G.S., Ort,C.A.: Neuronal control of swimming in the medicinal leech. I. Dynamics of the swimming rhythm. J. comp. Physiol. 94, 97–119 (1974a)
Kristan,W.B.,Jr., Stent,G.S., Ort,C.A.: Neuronal control of swimming in the medicinal leech. III. Impulse patterns of the motor neurons. J. comp. Physiol. 94, 155–176 (1974b)
Lewis,E.R.: Using electronic circuits to model simple neuroelectric interactions. Proc. Inst. Elec. Electron Engrs. 56, 931–949 (1968)
Ort,C.A., Kristan,W.B.,Jr., Stent,G.S.: Neuronal control of swimming in the medicinal leech. II. Identification and connections of motor neurons. J. comp. Physiol. 94, 121–154 (1974)
Perkel, D.H., Mulloney, B.: Motor pattern production in reciprocally inhibitory neurons exhibiting postinhibitory rebound. Science 185, 181–183 (1974)
Poon,M.: A neuronal network generating the swimming rhythm in the leech. Ph. D. Thesis, Univ. of California, Berkeley, Calif. 1976
Poon,M., Friesen,W.O., Stent,G.S.: Neural control of swimming in the medicinal leech. V. Connections between the oscillatory interneurons and the motor neurons. Submitted for publication (1977)
Pozin,N.V., Shulpin,Yu.A.: Analysis of the work of auto-oscillatory neurone junctions. Biofizika 15, 156–163 (1970)
Reiss,R.F.: A theory and simulation of rhythmic behavior due to reciprocal inhibition in small nerve nets. Am. Fed. Inf. Process Soc. Proc. Spring Joint Computer Conference 21, 171–194 (1962)
Székely,G.: Logical network for controlling limb movement in urodela. Acta Physiol. Acad. Sci. Hung. 27, 285–289 (1965)
Wilson,D.M.: Central nervous mechanisms for the generation of rhythmic behavior in arthropods. In: Nervous and hormonal mechanisms of integration. Symp. Soc. Exp. Biol. 20, 199–228 (1966)
Wilson,D.M., Waldron,I.: Models for the generation of the motor output pattern in flying locusts. Proc. Inst. Elec. Electron, Engrs. 56, 1058–1064 (1968)
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Friesen, W.O., Stent, G.S. Generation of a locomotory rhythm by a neural network with recurrent cyclic inhibition. Biol. Cybernetics 28, 27–40 (1977). https://doi.org/10.1007/BF00360911
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DOI: https://doi.org/10.1007/BF00360911