Abstract
GPD genes encoding glyceraldehyde-3-phosphate dehydrogenase were isolated from the homobasidiomycetes Schizophyllum commune, Phanerochaete chrysosporium and Agaricus bisporus. All three species contain one transcriptionally active GPD gene, but A. bisporus also contains an inactive GPD gene (tandemly linked to the active gene). These genes contain 5–9 introns located at conserved positions, differing (except in one case) from intron positions in ascomycetous GPD genes. The predicted amino-acid sequences of the proteins encoded by the three active GPD genes are highly homologous. A comparison with protein sequences from filamentous ascomycetes shows a clear distinction, whereas the GPD genes from ascomycetous yeasts are quite distinct from both the filamentous ascomycetes and basidiomycetes. Promoter regions of ascomycetous GPD genes do not correspond to those of the GPD genes of basidiomycetes which may (partly) explain poor expression in basidiomycetes of introduced genes driven by an ascomycete GPD promoter.
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References
Alic M, Clark EK, Kornegay JR, Gold MH (1990) Curr Genet 17:305–311
Arcari P, Martinelli R, Salvatore F (1984) Nucleic Acids Res 12:9179–9189
Barrett V, Dixon RK, Lemke PA (1990) Appl Microbiol Biotechnol 33:313–316
Brinkmann H, Martinez P, Quigley F, Martin WF, Cerff R (1987) J Mol Evol 26:320–328
Casselton LA, de la Fuente Herce A (1989) Curr Genet 16:35–40
Challen MP, Rao BG, Elliott TJ (1991) In: Van Griensven LJLD (ed) Genetics and breeding of Agaricus. Pudoc, Wageningen, pp 129–135
Choi GH, Nuss DL (1990) Nucleic Acids Res 18:5566
Church GM, Gilbert W (1984) Proc Natl Acad Sci USA 81:1991–1995
Davidson BE, Sajgo M, Noller HF, Harris JI (1967) Nature 216:1181–1185
Dons JJM, De Vries OMH, Wessels JGH (1979) Biochim Biophys Acta 563:100–112
Edens LE, Bom J, Ledeboer AM, Maat J, Toonen MY, Visser C, Verrips CT (1984) Cell 37:629–633
Fitch WM, Margoliash E (1967) Science 155:279–284
Goudot-Crozel V, Caillol D, Djabali M, Dessein AJ (1989) J Exp Med 170:2065–2080
Gurr SJ, Unkles SE, Kinghorn JR (1987) In: Kinghorn JR (ed) Gene structure in eukaryotic microbes. IRL Press, Oxford pp 93–139
Harmsen MC, Scheer J, Schuurs TA, Wessels JGH (1991) In: Van Griensven LJLD (ed) Genetics and breeding of Agaricus. Pudoc, Wageningen, pp 140–145
Higgins DG, Sharp Pm (1988) Gene 73:237–244
Holland MJ, Holland JP (1978) Biochemistry 17:4900–4907
Holland JP, Holland MJ (1979) J Biol Chem 254:9839–9845
Holland MJ, Holland JP (1980) J Biol Chem 255:2596–2605
Holland JP, Labieniec L, Swimmer C, Holland MJ (1983) J Biol Chem 258:5291–5299
Horgen PA, Arthur R, Davy O, Moum A, Herr F, Strauss N, Anderson J (1984) Can J Microbiol 30:587–593
Huang XY, Barrios LAM, Vonkhorporn P, Honda S, Albertson DG, Hecht RM (1989) J Mol Biol 206:411–424
Hynes MJ (1989) Exp Mycol 13:196–198
Imura T, Utatsu I, Toh-E A (1987) Agric Biol Chem 51:1641–1647
Krebs EG (1952) J Biol Chem 200:471–478
Lake JA (1987) Mol Biol Evol 4:167–191
Martin WF, Cerff R (1986) Eur J Biochem 159:323–331
Michels PAM, Marchand M, Kohl L, Allert S, Wierenga K, Opperdoes FR (1991) Eur J Biochem 198:421–428
Mooibroek H, Kuipers AGJ, Sietsma JH, Punt PJ, Wessels JGH (1990) Mol Gen Genet 222:41–48
Myers EW, Miller W (1988) Cabios 4:11–17
Osiewacz HD, Ridder R (1991) Curr Genet 20:151–155
Punt PJ, Dingemanse MA, Jabobs-Meijsing BJM, Pouwels PH, van den Hondel CAMJJ (1988) Gene 69:49–57
Punt PJ, Dingemanse MA, Kuyvenhoven A, Soede RDM, Pouwels PM, van den Hondel CAMJJ (1990) Gene 93:101–109
Raeder U, Broda P (1984) Curr Genet 8:499–506
Royer JC, Horgen PA (1991) IN: Van Griensven LJLD (ed) Genetics and breeding of Agaricus. Pudoc, Wageningen, pp 135–140
Russell DA, Sachs MM (1989) The Plant Cell 1:793–803
Schrank A, Tempelaars C, Sims PFG, Oliver SG, Broda P (1991) Mol Microbiol 5:467–476
Schuren FHJ, Wessels JGH (1990) Gene 90:199–205
Shih MC, Lazar G, Goodman HM (1986) Cell 47:73–80
Shuster JR (1990) Nucleic Acids Res 18:4271
Smith TL (1989) Proc Natl Acad Sci USA 86:7063–7066
Smith TL, Leong SA (1990) Gene 93:111–117
Stone EM, Rothblum KN, Alevy MC, Kuo TM, Schwartz RJ (1985) Proc Natl Acad Sci USA 82:1628–1632
Tabor S, Richardson C (1987) Proc Natl Acad Sci USA 84:4767–4771
Tso JY, Sun XH, Wu R (1985) J Biol Chem 260:8220–8228
Vincent S, Fort P (1990) Nucleic Acids Res 18:3054
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Harmsen, M.C., Schuren, F.H.J., Moukha, S.M. et al. Sequence analysis of the glyceraldehyde-3-phosphate dehydrogenase genes from the basidiomycetes Schizophyllum commune, Phanerochaete chrysosporium and Agaricus bisporus . Curr Genet 22, 447–454 (1992). https://doi.org/10.1007/BF00326409
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DOI: https://doi.org/10.1007/BF00326409