Summary
Early morphogenesis of the brain and its derivatives was studied in sixty-nine baboon and rhesus monkey embryos representing developmental stages 8–16, and compared with the staged human embryo. The baboon and rhesus monkey embryos develop in a similar temporal sequence when compared with human embryos with the following exceptions: 1) The respective developmental events for otic disc, adenohypophyseal pouch, and hippocampal internal sulcus formation in the baboon and rhesus monkey occur at stage 10, stages 11–12, and after stage 16, while the comparable stages in humans are 9, 10, and 16; 2) Alternatively, formation of the trigeminal primordium and the motor root of the trigeminal nerve and evagination of the neurohypophysis occur earlier in the baboon and rhesus monkey (i.e., stages 12–13, stage 14, and stage 15, respectively) than observed in the human embryo (stage 14, stage 15, and stage 16, respectively); and 3) Lens pore closure in baboon and human embryos takes place during stage 14, while in the rhesus monkey closure occurs during stage 15.
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Bartelmez GW, Dekaban AS (1962) The early development of the human brain. Contr Embryol Carneg Inst 37:13–32
Bartelmez GW, Evans HM (1926) The development of the human embryo during the period of somite formation, including embryos with 2 to 16 pairs of somites. Contr Embryol Carneg Inst 17:1–67
Gasser RF (1967) The development of the facial nerve in man. Ann Otol Rhinol Laryngol 76:37–57
Gasser RF (1975) Atlas of human embryos. Harper and Row Inc, Hagerstown, Maryland
Gasser RF, Hendrickx AG (1967) The development of the facial nerve in baboon embryos (Papio sp.). J Comp Neurol 129:203–218
Gasser RF, Hendrickx AG (1969) The development of the trigeminal nerve in baboon embryos (Papio sp.). J Comp Neurol 136:159–182
Gilbert C, Heuser CH (1954) Studies in the development of the baboon (Papio ursinus). Contr Embryol Carneg Inst 35:11–54
Hartman CG (1932) Studies in the reproduction of the monkey Macaca (Pithecus) rhesus, with special references to menstruation and pregnancy. Contr Embryol Carneg Inst 23:1–161
Hartman CG (1944) Regeneration of the monkey uterus after surgical removal of the endometrium and accidental endometriosis. West J Surg Obstet Gynecol 52:87–102
Heard OO (1957) Methods used by C.H. Heuser in preparing and sectioning early embryos. Contr Embryol Carneg Inst 36:1–18
Hendrickx AG, Sawyer RH (1975) Embryology of the rhesus monkey. In: Bourne GH (ed), The rhesus monkey. Academic Press, New York, Vol 2
Hendrickx AG, Houston ML, Kraemer DC, Gasser RF, Bollert JA (1971) Embryology of the baboon. University of Chicago Press, Chicago
Heuser CH, Streeter GL (1941) Development of the macaque embryo. Contr Embryol Carneg Inst 29:15–55
Hines M (1922) Studies in the growth and differentiation of the telencephalon in man. The fissura hippocampi. J Comp Neurol 34:73–171
Humphrey T (1968) The development of the human amygdala during early embryonic life. J Comp Neurol 132:135–165
O'Rahilly R (1963) The early embryology of the otic vesicle in staged human embryos. J Embryol Exp Morphol 11:741–755
O'Rahilly R (1966) The early development of the eye in staged human embroys. Contr Embryol Carneg Inst 38:1–42
O'Rahilly R (1973) Developmental stages in human embryos. Part A: Embryos of the first three weeks (stages 1–9). Carneg Inst Wash Pub 631
O'Rahilly R, Gardner E (1971) The timing and sequence of events in the development of the human nervous system during the embryonic period proper. Anat Embryol 134:1–12
Sawyer RH, Wilson DB, Anderson J, Hendrickx AG (1974) Incorporation of 3H-thymidine in rhesus monkey (Macaca mulatta) embryos. J Exp Zool 189:121–126
Streeter GL (1912) The development of the nervous system. In: Keilbel F, Mall FD (eds) Manual of human embryology. JG Lippincott Co, Philadelphia, Vol 2
Streeter GL (1942) Developmental horizons in human embryos. Description of age group XI, 13 to 20 somites, and age group XII, 21 to 29 somites. Contr Embryol Carneg Inst 30:211–245
Streeter GL (1945) Developmental horizons in human embryos. Description of age group XIII, embryos about 4 or 5 millimeters long, and age group XIV, period of indentation of the lens vesicle. Contr Embryol Carneg Inst 31:27–63
Streeter GL (1948) Development horizons in human embryos. Description of age groups XV, XVI, XVII, and XVIII. Contr Embryol Carneg Inst 34:165–196
Streeter GL (1951) Developmental horizons in human embryos. Description of age groups XIX, XX, XXI, XXII, and XXIII, being the fifth issue of a survey of the Carnegie collection. Contr Embryol Carneg Inst 34:165–196
Van Campenhout E (1948) La contribution des placodes épiblastiques au dévelopement des ganglions des nerfs craniens chez l'embryon humain. Arch Biol 59:253–266
Wilson DB, Hendrickx AG (1977) Quatitative aspects of proliferation in the nasal epithelium of the rhesus monkey embryo. J Embryol Exp Morphol 38:217–226
Wilson DB, Sawyer RH, Hendrickx AG (1975) Proliferation gradients in the inner ear of the monkey (Macaca mulatta) embryo. J Comp Neurol 164:23–29
Wilson DB, Hendrickx AG, Sawyer RH (1976) Distribution of (3H)thymidine in the lens of the rhesus monkey (Macaca mulatta) embryo. Exp Eye Res 23:417–423
Yokoh Y (1968) The early development of the nervous system in man. Acta Anat (Basel) 71:492–518
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Supported by NIH Grants HD08658 and RR00169
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Davignon, R.W., Parker, R.M. & Hendrickx, A.G. Staging of the early embryonic brain in the baboon (Papio cynocephalus) and rhesus monkey (Macaca mulatta). Anat. Embryol. 159, 317–334 (1980). https://doi.org/10.1007/BF00317654
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DOI: https://doi.org/10.1007/BF00317654