Abstract
The present study was undertaken to reveal the magnesium distribution in human bone. Sixty human ribs, obtained from subjects aged 10–80 years of age, were used. Transverse sections were prepared from the middle region of the human ribs. Adjacent sections were ground to a thickness of about 1000 μm. One section was used for magnesium determination by atomic absorption spectrophotometry, and the other was used for analysis with X-ray microanalysis. Thirty micron thick samples were abraded continuously from the periosteal and the endosteal surfaces by abrasive microsampling, as previously described by Weatherell et al. [3]. Results showed that magnesium concentrations were higher in both the periosteal and endosteal surfaces and did not change with age in general, although it tended to be higher among teenagers and lower over 80 years old.
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References
Bigi A, Foresti E, Gregorini R, Ripamonti A, Roveri N, Shah JS (1992) The role of magnesium on the structure of biological apatite. Calcif Tissue Int 50:439–444
Zipkin I, McClure FJ, Lee WA (1960) Relation of the fluoride content of human bone to its chemical composition. Arch Oral Biol 2:190–195
Weatherell JA, Robinson C, Strong M, Nakagaki H (1985) Micro-sampling by abrasion. Caries Res 19:97–102
Marier JR (1991) Intake of magnesium and fluoride, and some systemic effects. Proc of The Finnish Dental Society 87:581–594
Narita N, Kato K, Nakagaki H, Sakakibara Y, Ohno N, Kameyama Y, Weatherell JA (1990) Distribution of fluoride concentration in the rat bone. Calcif Tissue Int 46:200–204
Zipkin I (1966) The chemical composition of bones, teeth, calculus, saliva and the periodontium of the human in the science of nutrition and its application in clinical dentistry. Nizel A (ed) WB Saunders, Philadelphia, p 282
Merck Index (1983) p 502
Sokal RR, Rohlf FJ (1981) Biomrtry, 2nd ed. Freeman, New York, pp. 128–178; 374–387
Weiner S, Traub W (1992) Bone structure: from ängstroms to microns. FASEB J 6:879–885
Cohen L, Kitzes R (1981) Infrared spectroscopy and magnesium content of bone mineral in osteoporotic women. Israel J Med Sci 17:1123–1125
Burny F, Wollast R (1972) Study of bone mineralization at the microscopic level using the electron probe microanalyser. Sodium and magnesium distribution in normal bone. Acta Orthop Belg 38:79–84
Ishiguro K, Nakagaki H, Tsuboi S, Narita N, Kato K, Li J, Kamei H, Yoshioka I, Miyauchi K, Hosoe H, Shimano R, Weatherell JA, Robinson C (1993) Distribution of fluoride in cortical bone of human rib. Calcif Tissue Int 52:278–282