Summary
334 necropsy reports of intracranial neoplasm from an autopsy material over 13 years were reviewed to study the relationship of intracranial tumors to vascular thrombosis. The incidence of venous thrombosis in intracranial tumors was found to be 27.5% while that of a control group without malignancies taken at random from the autopsy material was 17%. The difference gives a statistical significance of P ≦ 0.05. The parameters of sex, surgical intervention, the malignancy and the histological type of the tumor apparently do not affect thrombus formation to a statistically significant degree. There is increased thrombosis frequency with increasing age. The presence of hemiparesis or hemiparalysis does not affect the incidence of thrombosis. However, it determines to a great degree the lateralization of the thrombus.
Zusammenfassung
Aus den Sektionsprotokollen, die einen Zeitraum von 13 Jahren umfaßten, wurden insgesamt 334 Fälle mit Hirntumoren herausgesucht, um die Beziehung zwischen intrakraniellen Tumoren und vasculären Thrombosen zu untersuchen. Die Koincidenz von venösen Thrombosen und intrakraniellen Tumoren ergibt sich zu 27.5%, die Thrombosehäufigkeit in einer zufällig ausgewählten Kontrollgruppe ohne Tumoren jedoch nur zu 17%. Der Unterschied ist statistisch signifikant auf dem P ≦ 0,05-Niveau. Eine statistische Signifikanz hinsichtlich verschiedener Faktoren wie Geschlecht, Operation, Malignität und histologischer Typ des Tumors ist nicht gegeben. Die Thrombosehäufigkeit steigt mit zunehmendem Alter an. Die Existenz von Hemiparesen oder Hemiparalysen beeinflußt nicht die Thrombosefrequenz, jedoch bestimmen sie in starkem Maß die Lokalisation der Thrombose.
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Kayser-Gatchalian, M.C., Kayser, K. Thrombosis and intracranial tumors. J. Neurol. 209, 217–224 (1975). https://doi.org/10.1007/BF00312543
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DOI: https://doi.org/10.1007/BF00312543