Abstract
We report seven cases of spinal cord compression resulting from Burkitt lymphoma in boys aged 15 years and below. This became manifest clinically as acute or rapidly progressive spinal cord compression. All the patients showed total paraplegia with a sensory loss at thoracic level and sphincter disturbances. Four patients were operated on, the operation permitting exeresis of an epidural tumor. In three cases surgery was followed by chemotherapy. One patient was treated exclusively with chemotherapy. Owing to the effectiveness of chemotherapy, surgery should be considered only in cases of rapid deterioration or for diagnostic purposes.
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References
Berard CW (1985) Morphological definition of Burkitt's tumour: historical review and present status. IARC Sci Publ 60:31–35
Burkitt D (1958) A sarcoma involving the jaws in African children. Br J Surg 46:218–224
Dreyfus (1992) L'hématologie. Flammarion, Paris
Knowles DM, Chamulak GA, Subar M, Burke JS, Dugan M, Wernz J, Slymotzky C, Pelicci G, Dalla-Favera R, Raphael B (1988) Lymphoid neoplasia associated with AIDS. Ann Int Med 744–753
Lenoir GM, Philip T, Sohier R (1984) Burkitt's type lymphoma. EBV association and cytogenetic markers in cases from various geographic origins: environmental influences in the pathogenesis of leukemias and lymphomas. Raven Press, New York, pp 282–295
Lyons M, O'Neil BP, Marsh R, Kurtin PJ (1992) Primary spinal epidural non-Hodgkin's lymphoma: report of eight patients and review of the literature. Neurosurgery 30:675–680
Magrath IT, Sarigan E (1985) Clinical features of Burkitt's lymphoma in the USA. IARC Sci Publ 60:119–127
Miyoshi I (1983) Japanese Burkitt's lymphoma: clinicopathological review of 14 cases. Jpn J Clin Oncol 13:489–496
Mizugami T, Mikata A, Hajikano H, Asanuma K, Ishida H, Chisado C (1987) Primary spinal epidural Burkitt's lymphoma. Surg Neurol 28:158–162
N'Kruhma FK, Olweny CLN (1985) Clinical features of Burkitt's lymphoma: the african experience. IARC Sci Publ 60:87–95
O'Conor GT, Rappaport H, Smith EB (1965) Childhood lymphoma resembling Burkitt's tumor in the United States. Cancer 18:330–333
Odeku EC, Osuntokun BO (1968) The clinical neurology of Burkitt's neoplasm. A prelimary evaluation based on 105 cases. West Afr Med J 27:263–267
Parkin DM, Sohier R, O'Conor GT (1985) Geographic distribution of Burkitt's lymphoma. IARC Sci Publ 60:55–164
Patte C, Philip T, Rodary C, Zucker JM, Behrendt H, Gentel JC, Lamagnere JP, Otten J, Dufillot D, Pein F, Caillou B, Lemule J (1991) High survival rate in advanced-stage B-cell lymphomas and leukemias without CNS involvement with a short intensive polychemotherapy: results from the French Pediatric Oncology Society of a randomized trial of 216 children. J Clin Oncol 9:123–132
Patte C, Michon J, Leverger G, Frappaz D, Robert A, Bertrand Y, Perel Y, Behrendt H, Gentel JC, Thyss A (1993) High survival rate of childhood B-cell lymphoma and leukemia (ALL) as result of the LMB 89 protocol of the SFO (abstract). Med Pediatr Oncol 21:531
Philip T (1985) Clinical and therapy of Burkitt's lymphoma in the world. IARC Sci Publ 60:465–468
Philip T, Lenoir GM, Favrot M, Philip I (1986) Le lymphome de Burkitt. Encyclopédie des cancers. Hémopathies malignes. Flammarion Paris, pp 437–447
Sariban E, Edwards S, Janus C, Magrath I (1983) Central nervous system involvement in American Burkitt's lymphoma. J Clin Oncol 1:677–680
Raffel C, Neave VCD, Lavine S, McComb JG (1991) Treatment of spinal cord compression by epidural malignancy in child hood. Neurosurgery 28:349–352
Tekkok IH, Tahta K, Erbengi A, Buyukpamukcu M, Ruacan S, Topcu M (1991) Primary intracranial extradural Burkitt-type lymphoma. Child's Nerv Syst 7:172–174
Tubiana M, Tursz T (1987) La maladie de Burkitt. Ann Pédiatr (Paris) 34:267–271
Turgut M, Ozlan OE, Erbengi A (1991) Burkitt's lymphoma: an unusual cause of childhood paraplegia. Child's Nerv Syst 7:168–171
Ziegler JL (1981) Burkitt's lymphoma. N Engl J Med 13:735–744
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Dechambenoit, G., Piquemal, M., Giordano, C. et al. Spinal cord compression resulting from Burkitt's lymphoma in children. Child's Nerv Syst 12, 210–214 (1996). https://doi.org/10.1007/BF00301252
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DOI: https://doi.org/10.1007/BF00301252